BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/MAP2K1
MOLECULAR TARGETUniProt: Q02750

MAP2K1

mitogen-activated protein kinase kinase 1

153 compounds · BiohacksAI corpus v20260307-01

153
compounds
Compounds
153
Gene Symbol
MAP2K1
NCBI Gene
5604

Looking for compounds that interact with MAP2K1?

View all 153 compounds →
About MAP2K1

MAP2K1 (mitogen-activated protein kinase kinase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 153 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MAP2K1 on UniProt →
Compounds Targeting MAP2K1 (50)
1
Tofacitinib
4.65
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Ruxolitinib
4.23
confidence
6
Bosutinib
4.08
confidence
7
Neratinib
3.66
confidence
8
Nintedanib
3.61
confidence
9
Naphthoquinone
3.58
confidence
10
Canertinib
3.53
confidence
11
Pelitinib
3.50
confidence
12
Tae 684
3.43
confidence
13
Gilteritinib
3.40
confidence
14
Fedratinib
3.40
confidence
15
Trametinib
296
studies
3.22
confidence
16
Mirdametinib
3.18
confidence
17
Jnj 7706621
3.09
confidence
18
Dovitinib
3.09
confidence
19
Selumetinib
3.09
confidence
20
Lestaurtinib
3.04
confidence
21
Hymenialdisine
3.00
confidence
22
Ci 1040
2.94
confidence
23
Orantinib
2.89
confidence
24
Defosbarasertib
2.89
confidence
25
K 252a
2.83
confidence
26
R 406
2.83
confidence
27
Oroidin
2.77
confidence
28
Plx 4720
2.71
confidence
29
Pha 665752
2.71
confidence
30
Kw 2449
2.64
confidence
31
Cobimetinib
2.64
confidence
32
Linsitinib
2.64
confidence
33
Debromohymenialdisine
2.56
confidence
34
Tak 285
2.40
confidence
35
Azd 7762
2.30
confidence
36
Binimetinib
2.30
confidence
37
Avutometinib
2.30
confidence
38
Su 014813
2.20
confidence
39
Amg 900
2.08
confidence
40
Cep 32496
1.95
confidence
41
Tak 733
1.95
confidence
42
Gsk 1059615
1.95
confidence
43
Pd98059
7
studies
1.79
confidence
44
Dasatinib
299
studies
1.10
confidence
45
Allium Sativum
500
studies
1.00
confidence
46
Aloe Vera
1.00
confidence
47
Artemisia Argyi
1.00
confidence
48
Artemisia Capillaris
1.00
confidence
49
Agastache Rugosa
1.00
confidence
50
Allium Tuberosum
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.