BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B

Compounds That Target MAP4K1

Mitogen-activated protein kinase kinase kinase kinase 1 · 40 compounds in BiohacksAI corpus

MAP4K1 (Mitogen-activated protein kinase kinase kinase kinase 1) is a biological target with 40 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP4K1 modulation for therapeutic and biohacking applications.

All 40 Compounds — Ranked by Evidence
1
Alvocidib
4.52
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Ponatinib
4.26
confidence
6
Nilotinib
4.17
confidence
7
Bosutinib
4.08
confidence
8
Midostaurin
3.85
confidence
9
Pazopanib
3.69
confidence
10
Neratinib
3.66
confidence
11
Nintedanib
3.61
confidence
12
Pelitinib
3.50
confidence
13
Tae 684
3.43
confidence
14
Fedratinib
3.40
confidence
15
Gilteritinib
3.40
confidence
16
Linifanib
3.33
confidence
17
Bisindolylmaleimide Ix
3.14
confidence
18
Dovitinib
3.09
confidence
19
Jnj 7706621
3.09
confidence
20
At 9283
3.09
confidence
21
Lestaurtinib
3.04
confidence
22
Pacritinib
3.04
confidence
23
Pf 03758309
3.00
confidence
24
Ruboxistaurin
2.94
confidence
25
Danusertib
2.94
confidence
26
Orantinib
2.89
confidence
27
R 406
2.83
confidence
28
K 252a
2.83
confidence
29
Cediranib
2.83
confidence
30
Milciclib
2.77
confidence
31
Pf 00562271
2.77
confidence
32
Pha 665752
2.71
confidence
33
Kw 2449
2.64
confidence
34
Ast 487
2.56
confidence
35
Defactinib
2.48
confidence
36
Motesanib
2.48
confidence
37
Azd 7762
2.30
confidence
38
Su 014813
2.20
confidence
39
Rebastinib
2.20
confidence
40
Enzastaurin
2.08
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP4K1 (Mitogen-activated protein kinase kinase kinase kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP4K1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.