BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

MAP4K1

Mitogen-activated protein kinase kinase kinase kinase 1

40 compounds · BiohacksAI corpus v20260307-01

40
compounds
Compounds
40
Gene Symbol
MAP4K1
NCBI Gene

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About MAP4K1

MAP4K1 (Mitogen-activated protein kinase kinase kinase kinase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 40 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting MAP4K1 (40)
1
Alvocidib
4.52
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Ponatinib
4.26
confidence
6
Nilotinib
4.17
confidence
7
Bosutinib
4.08
confidence
8
Midostaurin
3.85
confidence
9
Pazopanib
3.69
confidence
10
Neratinib
3.66
confidence
11
Nintedanib
3.61
confidence
12
Pelitinib
3.50
confidence
13
Tae 684
3.43
confidence
14
Fedratinib
3.40
confidence
15
Gilteritinib
3.40
confidence
16
Linifanib
3.33
confidence
17
Bisindolylmaleimide Ix
3.14
confidence
18
Dovitinib
3.09
confidence
19
Jnj 7706621
3.09
confidence
20
At 9283
3.09
confidence
21
Lestaurtinib
3.04
confidence
22
Pacritinib
3.04
confidence
23
Pf 03758309
3.00
confidence
24
Ruboxistaurin
2.94
confidence
25
Danusertib
2.94
confidence
26
Orantinib
2.89
confidence
27
R 406
2.83
confidence
28
K 252a
2.83
confidence
29
Cediranib
2.83
confidence
30
Milciclib
2.77
confidence
31
Pf 00562271
2.77
confidence
32
Pha 665752
2.71
confidence
33
Kw 2449
2.64
confidence
34
Ast 487
2.56
confidence
35
Defactinib
2.48
confidence
36
Motesanib
2.48
confidence
37
Azd 7762
2.30
confidence
38
Su 014813
2.20
confidence
39
Rebastinib
2.20
confidence
40
Enzastaurin
2.08
confidence
Top 40 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.