Compounds That Target MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2 · 71 compounds in BiohacksAI corpus

MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2) is a biological target with 71 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP4K2 modulation for therapeutic and biohacking applications.

View MAP4K2 target page →UniProt: Q12851 ↗

Most Studied Compounds for MAP4K2

Carvedilol

296+

studies

All 50 Compounds — Ranked by Evidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Bms 777607

3.37

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Lenvatinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Orantinib

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Cediranib

2.83

confidence

Milciclib

2.77

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Tivozanib

2.64

confidence

Linsitinib

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Raf 265

2.48

confidence

Mk 5108

2.48

confidence

Gsk 461364

2.40

confidence

Azd 7762

2.30

confidence

Aee 788

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Rg 547

2.08

confidence

Amg 900

2.08

confidence

Cep 32496

1.95

confidence

Cerdulatinib

1.95

confidence

Pf 03814735

1.79

confidence

Ucn 01

1.79

confidence

Osi 632

1.79

confidence

Carvedilol

296+

studies

1.39

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP4K2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.