BiohacksAI/Targets/MAP4K2

MOLECULAR TARGETUniProt: Q12851

MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

71 compounds · BiohacksAI corpus v20260307-01

compounds

Compounds

Gene Symbol

MAP4K2

NCBI Gene

5871

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About MAP4K2

MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 71 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MAP4K2 on UniProt →

Compounds Targeting MAP4K2 (50)

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ponatinib

4.26

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Bms 777607

3.37

confidence

Dovitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Lenvatinib

3.04

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Orantinib

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Cediranib

2.83

confidence

Milciclib

2.77

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Tivozanib

2.64

confidence

Linsitinib

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Raf 265

2.48

confidence

Mk 5108

2.48

confidence

Gsk 461364

2.40

confidence

Azd 7762

2.30

confidence

Aee 788

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Rg 547

2.08

confidence

Amg 900

2.08

confidence

Cep 32496

1.95

confidence

Cerdulatinib

1.95

confidence

Pf 03814735

1.79

confidence

Ucn 01

1.79

confidence

Osi 632

1.79

confidence

Carvedilol

296

studies

1.39

confidence

Top 50 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.