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Compounds That Target MELK

maternal embryonic leucine zipper kinase · 154 compounds in BiohacksAI corpus

MELK (maternal embryonic leucine zipper kinase) is a biological target with 154 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MELK modulation for therapeutic and biohacking applications.

Most Studied Compounds for MELK
500+
studies
500+
studies
499+
studies
300+
studies
117+
studies
11+
studies
4+
studies
All 53 Compounds — Ranked by Evidence
1
Imatinib
5.47
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Ponatinib
4.26
confidence
5
Ruxolitinib
4.23
confidence
6
Midostaurin
3.85
confidence
7
Brigatinib
3.81
confidence
8
Neratinib
3.66
confidence
9
Fasudil
3.66
confidence
10
Nintedanib
3.61
confidence
11
Bms 387032
3.47
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Mln 8054
3.33
confidence
15
Dabrafenib
3.30
confidence
16
Dovitinib
3.09
confidence
17
At 9283
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Pf 03758309
3.00
confidence
20
Danusertib
2.94
confidence
21
K 252a
2.83
confidence
22
Hesperadin
2.77
confidence
23
Milciclib
2.77
confidence
24
Pf 00562271
2.77
confidence
25
Crenolanib
2.71
confidence
26
Kw 2449
2.64
confidence
27
Gsk 690693
2.64
confidence
28
Ast 487
2.56
confidence
29
Defactinib
2.48
confidence
30
Azd 7762
2.30
confidence
31
Su 014813
2.20
confidence
32
Bgt 226 Free Base
2.20
confidence
33
Su 11652
2.08
confidence
34
Cyc 116
2.08
confidence
35
Enzastaurin
2.08
confidence
36
Uprosertib
1.95
confidence
117+
studies
1.10
confidence
11+
studies
1.10
confidence
39
Cynomorium Songaricum
1.00
confidence
40
Ephedra Sinica
1.00
confidence
41
Chaenomeles Speciosa
1.00
confidence
42
Citrus Reticulata
1.00
confidence
500+
studies
1.00
confidence
500+
studies
1.00
confidence
45
Allium Tuberosum
1.00
confidence
46
Aloe Vera
1.00
confidence
47
Arctium Lappa
1.00
confidence
48
Artemisia Capillaris
1.00
confidence
49
Aster Tataricus
1.00
confidence
499+
studies
1.00
confidence
4+
studies
0.69
confidence
52
Pictilisibdrugage
0.69
confidence
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MELK (maternal embryonic leucine zipper kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MELK target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.