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B
MOLECULAR TARGETUniProt: Q14680

MELK

maternal embryonic leucine zipper kinase

41 compounds · BiohacksAI corpus v20260307-01

41
compounds
Compounds
41
Gene Symbol
MELK
NCBI Gene
9833

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About MELK

MELK (maternal embryonic leucine zipper kinase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 41 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MELK on UniProt →
Compounds Targeting MELK (41)
1
Imatinib
5.47
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Ponatinib
4.26
confidence
5
Ruxolitinib
4.23
confidence
6
Midostaurin
3.85
confidence
7
Brigatinib
3.81
confidence
8
Neratinib
3.66
confidence
9
Fasudil
3.66
confidence
10
Nintedanib
3.61
confidence
11
Bms 387032
3.47
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Mln 8054
3.33
confidence
15
Dabrafenib
3.30
confidence
16
Dovitinib
3.09
confidence
17
At 9283
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Pf 03758309
3.00
confidence
20
Danusertib
2.94
confidence
21
K 252a
2.83
confidence
22
Milciclib
2.77
confidence
23
Pf 00562271
2.77
confidence
24
Hesperadin
2.77
confidence
25
Crenolanib
2.71
confidence
26
Kw 2449
2.64
confidence
27
Gsk 690693
2.64
confidence
28
Ast 487
2.56
confidence
29
Defactinib
2.48
confidence
30
Azd 7762
2.30
confidence
31
Su 014813
2.20
confidence
32
Bgt 226 Free Base
2.20
confidence
33
Cyc 116
2.08
confidence
34
Enzastaurin
2.08
confidence
35
Su 11652
2.08
confidence
36
Uprosertib
1.95
confidence
11
studies
1.10
confidence
117
studies
1.10
confidence
4
studies
0.69
confidence
300
studies
0.69
confidence
41
Pictilisibdrugage
0
studies
0.69
confidence
Top 41 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.