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BiohacksAI/Targets/MELK
MOLECULAR TARGETUniProt: Q14680

MELK

maternal embryonic leucine zipper kinase

154 compounds · BiohacksAI corpus v20260307-01

154
compounds
Compounds
154
Gene Symbol
MELK
NCBI Gene
9833

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About MELK

MELK (maternal embryonic leucine zipper kinase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 154 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MELK on UniProt →
Compounds Targeting MELK (50)
1
Imatinib
5.47
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Ponatinib
4.26
confidence
5
Ruxolitinib
4.23
confidence
6
Midostaurin
3.85
confidence
7
Brigatinib
3.81
confidence
8
Neratinib
3.66
confidence
9
Fasudil
3.66
confidence
10
Nintedanib
3.61
confidence
11
Bms 387032
3.47
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Mln 8054
3.33
confidence
15
Dabrafenib
3.30
confidence
16
Dovitinib
3.09
confidence
17
At 9283
3.09
confidence
18
Lestaurtinib
3.04
confidence
19
Pf 03758309
3.00
confidence
20
Danusertib
2.94
confidence
21
K 252a
2.83
confidence
22
Hesperadin
2.77
confidence
23
Milciclib
2.77
confidence
24
Pf 00562271
2.77
confidence
25
Crenolanib
2.71
confidence
26
Kw 2449
2.64
confidence
27
Gsk 690693
2.64
confidence
28
Ast 487
2.56
confidence
29
Defactinib
2.48
confidence
30
Azd 7762
2.30
confidence
31
Su 014813
2.20
confidence
32
Bgt 226 Free Base
2.20
confidence
33
Su 11652
2.08
confidence
34
Cyc 116
2.08
confidence
35
Enzastaurin
2.08
confidence
36
Uprosertib
1.95
confidence
37
Sp600125
117
studies
1.10
confidence
38
Ha1077
11
studies
1.10
confidence
39
Cynomorium Songaricum
1.00
confidence
40
Ephedra Sinica
1.00
confidence
41
Chaenomeles Speciosa
1.00
confidence
42
Citrus Reticulata
1.00
confidence
43
Curcuma Longa
500
studies
1.00
confidence
44
Allium Sativum
500
studies
1.00
confidence
45
Allium Tuberosum
1.00
confidence
46
Aloe Vera
1.00
confidence
47
Arctium Lappa
1.00
confidence
48
Artemisia Capillaris
1.00
confidence
49
Aster Tataricus
1.00
confidence
50
Centella Asiatica
499
studies
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.