Compounds That Target PLK4

polo like kinase 4 · 64 compounds in BiohacksAI corpus

PLK4 (polo like kinase 4) is a biological target with 64 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PLK4 modulation for therapeutic and biohacking applications.

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Most Studied Compounds for PLK4

Axitinib

298+

studies

All 50 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Imatinib

5.47

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ruxolitinib

4.23

confidence

Ceritinib

4.19

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Nintedanib

3.61

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Bms 777607

3.37

confidence

Linifanib

3.33

confidence

Mln 8054

3.33

confidence

Dabrafenib

3.30

confidence

Alisertib

3.30

confidence

Tandutinib

3.22

confidence

Sp 600125

3.22

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Pf 03758309

3.00

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

Defosbarasertib

2.89

confidence

Momelotinib

2.89

confidence

Go 6976

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Cediranib

2.83

confidence

Pha 665752

2.71

confidence

Plx 4720

2.71

confidence

Enmd 2076

2.71

confidence

Kw 2449

2.64

confidence

Mk 5108

2.48

confidence

Merestinib

2.48

confidence

Axitinib

298+

studies

2.40

confidence

Ripasudil

2.40

confidence

Azd 7762

2.30

confidence

Bms 754807

2.30

confidence

Azd 1480

2.30

confidence

Su 014813

2.20

confidence

Rebastinib

2.20

confidence

Gsk 1070916

2.20

confidence

Decernotinib

2.20

confidence

Cyc 116

2.08

confidence

Asp 3026

2.08

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PLK4 (polo like kinase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PLK4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.