BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGET

PLK4

polo like kinase 4

64 compounds · BiohacksAI corpus v20260307-01

64
compounds
Compounds
64
Gene Symbol
PLK4
NCBI Gene
10733

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About PLK4

PLK4 (polo like kinase 4) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 64 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting PLK4 (50)
1
Erlotinib
5.55
confidence
2
Imatinib
5.47
confidence
3
Alvocidib
4.52
confidence
4
Foretinib
4.34
confidence
5
Tozasertib
4.33
confidence
6
Vandetanib
4.30
confidence
7
Ruxolitinib
4.23
confidence
8
Ceritinib
4.19
confidence
9
Midostaurin
3.85
confidence
10
Pazopanib
3.69
confidence
11
Nintedanib
3.61
confidence
12
Tae 684
3.43
confidence
13
Fedratinib
3.40
confidence
14
Gilteritinib
3.40
confidence
15
Bms 777607
3.37
confidence
16
Linifanib
3.33
confidence
17
Mln 8054
3.33
confidence
18
Dabrafenib
3.30
confidence
19
Alisertib
3.30
confidence
20
Tandutinib
3.22
confidence
21
Sp 600125
3.22
confidence
22
Jnj 7706621
3.09
confidence
23
At 9283
3.09
confidence
24
Lestaurtinib
3.04
confidence
25
Pf 03758309
3.00
confidence
26
Ruboxistaurin
2.94
confidence
27
Danusertib
2.94
confidence
28
Defosbarasertib
2.89
confidence
29
Momelotinib
2.89
confidence
30
Go 6976
2.89
confidence
31
R 406
2.83
confidence
32
K 252a
2.83
confidence
33
Cediranib
2.83
confidence
34
Pha 665752
2.71
confidence
35
Plx 4720
2.71
confidence
36
Enmd 2076
2.71
confidence
37
Kw 2449
2.64
confidence
38
Mk 5108
2.48
confidence
39
Merestinib
2.48
confidence
298
studies
2.40
confidence
41
Ripasudil
2.40
confidence
42
Azd 7762
2.30
confidence
43
Bms 754807
2.30
confidence
44
Azd 1480
2.30
confidence
45
Su 014813
2.20
confidence
46
Rebastinib
2.20
confidence
47
Gsk 1070916
2.20
confidence
48
Decernotinib
2.20
confidence
49
Cyc 116
2.08
confidence
50
Asp 3026
2.08
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.