Compounds That Target ROCK1

Rho associated coiled-coil containing protein kinase 1 · 46 compounds in BiohacksAI corpus

ROCK1 (Rho associated coiled-coil containing protein kinase 1) is a biological target with 46 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ROCK1 modulation for therapeutic and biohacking applications.

View ROCK1 target page →

Most Studied Compounds for ROCK1

Harmine

300+

studies

Crizotinib

298+

studies

Sp600125

117+

studies

Alsterpaullone

12+

studies

Ha1077

11+

studies

Kenpaullone

studies

Bdb Chembl3401984

studies

Bdb Chembl3401987

studies

All 46 Compounds — Ranked by Evidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Fasudil

3.66

confidence

Baricitinib

3.56

confidence

Y 27632

3.47

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Ha1077

11+

studies

3.18

confidence

Dovitinib

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Momelotinib

2.89

confidence

R 406

2.83

confidence

Capivasertib

2.77

confidence

Kw 2449

2.64

confidence

Gsk 690693

2.64

confidence

Ast 487

2.56

confidence

Zotiraciclib

2.56

confidence

Gsk 461364

2.40

confidence

Ripasudil

2.40

confidence

Hydroxyfasudil

2.40

confidence

Belumosudil

2.30

confidence

Su 014813

2.20

confidence

Decernotinib

2.20

confidence

Y 39983

2.20

confidence

Rg 547

2.08

confidence

Gsk 269962a

2.08

confidence

Gsk 180736a

2.08

confidence

Uprosertib

1.95

confidence

Sel 120 Free Base

1.95

confidence

Lx 7101

1.95

confidence

Netarsudil

1.95

confidence

Ucn 01

1.79

confidence

Ilorasertib

1.79

confidence

Afuresertib

1.79

confidence

Sar 407899 Free Base

1.79

confidence

Alsterpaullone

12+

studies

0.69

confidence

Crizotinib

298+

studies

0.69

confidence

Harmine

300+

studies

0.69

confidence

Kenpaullone

studies

0.69

confidence

Sp600125

117+

studies

0.69

confidence

Bdb Chembl3401984

studies

0.69

confidence

Bdb Chembl3401987

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ROCK1 (Rho associated coiled-coil containing protein kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ROCK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.