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Compounds That Target SCN5A

sodium voltage-gated channel alpha subunit 5 · 111 compounds in BiohacksAI corpus

SCN5A (sodium voltage-gated channel alpha subunit 5) is a biological target with 111 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into SCN5A modulation for therapeutic and biohacking applications.

Most Studied Compounds for SCN5A
993+
studies
500+
studies
500+
studies
500+
studies
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
All 60 Compounds — Ranked by Evidence
1
Carbamazepine
5.34
confidence
2
Propafenone
4.53
confidence
3
Mibefradil
4.26
confidence
4
Mexiletine
3.99
confidence
5
Loperamide
3.93
confidence
6
Gsk2879552
3.14
confidence
7
Tetrodotoxin
3.14
confidence
8
Nn Hexamethyleneamiloride
2.56
confidence
9
Pf 05089771
2.40
confidence
10
Gsk778
2.08
confidence
11
Mexiletine Hydrochloride
1.95
confidence
298+
studies
1.61
confidence
300+
studies
1.39
confidence
300+
studies
1.10
confidence
993+
studies
1.10
confidence
300+
studies
1.10
confidence
299+
studies
1.10
confidence
297+
studies
1.10
confidence
299+
studies
1.10
confidence
297+
studies
1.10
confidence
21
Nebivololdrugage
1.10
confidence
1.00
confidence
23
Cnidium Monnieri
1.00
confidence
24
Fritillaria Cirrhosa
1.00
confidence
25
Gastrodia Elata
1.00
confidence
299+
studies
1.00
confidence
27
Glycine Max
1.00
confidence
28
Morus Alba
1.00
confidence
300+
studies
1.00
confidence
30
Panax Notoginseng
1.00
confidence
31
Perilla Frutescens
1.00
confidence
32
Pinellia Ternata
1.00
confidence
33
Poria Cocos
1.00
confidence
500+
studies
1.00
confidence
500+
studies
1.00
confidence
36
Rehmannia Glutinosa
1.00
confidence
37
Schisandra Chinensis
1.00
confidence
38
Tussilago Farfara
1.00
confidence
498+
studies
1.00
confidence
40
Ziziphus Jujuba
1.00
confidence
41
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
43
Allium Tuberosum
1.00
confidence
44
Aloe Vera
1.00
confidence
45
Artemisia Annua
1.00
confidence
46
Bupleurum Chinense
1.00
confidence
300+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence
2+
studies
0.69
confidence
299+
studies
0.69
confidence
58
0.69
confidence
59
0.69
confidence
296+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for SCN5A (sodium voltage-gated channel alpha subunit 5). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: SCN5A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.