BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/SCN5A
MOLECULAR TARGETUniProt: Q14524

SCN5A

sodium voltage-gated channel alpha subunit 5

111 compounds · BiohacksAI corpus v20260307-01

111
compounds
Compounds
111
Gene Symbol
SCN5A
NCBI Gene
6331

Looking for compounds that interact with SCN5A?

View all 111 compounds →
About SCN5A

SCN5A (sodium voltage-gated channel alpha subunit 5) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 111 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View SCN5A on UniProt →
Compounds Targeting SCN5A (50)
1
Carbamazepine
5.34
confidence
2
Propafenone
4.53
confidence
3
Mibefradil
4.26
confidence
4
Mexiletine
3.99
confidence
5
Loperamide
3.93
confidence
6
Gsk2879552
3.14
confidence
7
Tetrodotoxin
3.14
confidence
8
Nn Hexamethyleneamiloride
2.56
confidence
9
Pf 05089771
2.40
confidence
10
Gsk778
2.08
confidence
11
Mexiletine Hydrochloride
1.95
confidence
12
Quinidine
298
studies
1.61
confidence
13
Saxitoxin
300
studies
1.39
confidence
14
Propranolol
300
studies
1.10
confidence
15
Duloxetine
993
studies
1.10
confidence
16
Aconitine
300
studies
1.10
confidence
17
Amitriptyline
299
studies
1.10
confidence
18
Flecainide
297
studies
1.10
confidence
19
Lidocaine
299
studies
1.10
confidence
20
Ranolazine
297
studies
1.10
confidence
21
Nebivololdrugage
0
studies
1.10
confidence
22
Nelumbo Nucifera
0
studies
1.00
confidence
23
Cnidium Monnieri
1.00
confidence
24
Fritillaria Cirrhosa
1.00
confidence
25
Gastrodia Elata
1.00
confidence
26
Ginkgo Biloba
299
studies
1.00
confidence
27
Glycine Max
1.00
confidence
28
Morus Alba
1.00
confidence
29
Panax Ginseng
300
studies
1.00
confidence
30
Panax Notoginseng
1.00
confidence
31
Perilla Frutescens
1.00
confidence
32
Pinellia Ternata
1.00
confidence
33
Poria Cocos
1.00
confidence
34
Portulaca Oleracea
500
studies
1.00
confidence
35
Raphanus Sativus
500
studies
1.00
confidence
36
Rehmannia Glutinosa
1.00
confidence
37
Schisandra Chinensis
1.00
confidence
38
Tussilago Farfara
1.00
confidence
39
Zingiber Officinale
498
studies
1.00
confidence
40
Ziziphus Jujuba
1.00
confidence
41
Agastache Rugosa
1.00
confidence
42
Allium Sativum
500
studies
1.00
confidence
43
Allium Tuberosum
1.00
confidence
44
Aloe Vera
1.00
confidence
45
Artemisia Annua
1.00
confidence
46
Bupleurum Chinense
1.00
confidence
47
Veratridine
300
studies
0.69
confidence
48
Bdb N 7 3r 5r 7r Adamantan 1 Ylmethoxy 6 Cyclopropyl 1 2 4 Triazolo 4 3 A Pyridin 3
2
studies
0.69
confidence
49
Bdb N 7 Adamantan 1 Ylmethoxy 6 Ethyl 1 2 4 Triazolo 4 3 A Pyridin 3 Yl Cyclopropane
2
studies
0.69
confidence
50
Bdb Chembl4061129
2
studies
0.69
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.