Compounds That Target TP53
tumor protein p53 · 153 compounds in BiohacksAI corpus
TP53 (tumor protein p53) is the most frequently mutated gene in human cancer and functions as a critical regulator of cell cycle arrest, DNA repair, and apoptosis. It acts as a transcription factor that responds to cellular stress, DNA damage, and oncogenic signals. The 153 compounds with documented TP53 interactions include both p53 activators relevant to cancer biology and natural compounds studied for their chemopreventive properties.
The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TP53 (tumor protein p53). Confidence scores reflect the strength and breadth of experimental evidence.
Explore related resources: TP53 target overview · All biological targets · Biological pathways
Data from BindingDB and PubMed. For research purposes only. Not medical advice.