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BiohacksAI/Pathways/Telomere Maintenance/Compounds
PATHWAYGenomic Stability

Compounds for Telomere Maintenance

Telomere length and telomerase activity — biomarker of cellular aging

312 compounds · ranked by PubMed study count

312
compounds
Showing all 312 compounds← Pathway overview

The following 312 compounds have been studied in relation to the Telomere Maintenance pathway. Rankings are based on total PubMed study count and evidence scores from the BiohacksAI corpus. MeSH terms: Telomere, Telomerase, Telomere Shortening.

All Compounds — Telomere Maintenance (312)
1
Pembrolizumab
1,000
studies
73.3
evidence
2
Insulin
1,000
studies
70.5
evidence
3
Sitagliptin
990
studies
72.1
evidence
4
Oryza_sativa
500
studies
37.0
evidence
5
Ribose
300
studies
54.3
evidence
6
Cucumis_sativus
500
studies
40.0
evidence
7
Momordica_charantia
500
studies
38.6
evidence
8
Prunus_avium
500
studies
42.2
evidence
9
Terminalia_chebula
500
studies
39.0
evidence
10
Linum_usitatissimum
499
studies
41.4
evidence
11
Folate
297
studies
57.9
evidence
12
Selenium
299
studies
56.8
evidence
13
Vitamin_b12
490
studies
60.3
evidence
14
Rapamycin
300
studies
55.4
evidence
15
Inositol
300
studies
54.7
evidence
16
Resveratrol
298
studies
52.1
evidence
17
Taurine
300
studies
46.2
evidence
18
Vitamin_b_12
466
studies
58.1
evidence
19
Silymarin
300
studies
48.7
evidence
20
Spermidine
241
studies
43.6
evidence
21
Pterostilbene
299
studies
39.6
evidence
22
Ergothioneine
300
studies
43.1
evidence
23
Shelterin_complex
300
studies
44.3
evidence
24
Recq_helicases
300
studies
43.1
evidence
25
Dna_helicases
300
studies
43.9
evidence
26
Dna_primers
300
studies
44.1
evidence
27
Extrachromosomal_dna
300
studies
45.2
evidence
28
Chromomycin_a3
300
studies
42.8
evidence
29
Dna_repair_enzymes
300
studies
40.3
evidence
30
Holoenzymes
300
studies
43.2
evidence
31
Bone_morphogenetic_protein_7
300
studies
45.3
evidence
32
Elements
300
studies
41.2
evidence
33
Plumbagin
300
studies
37.2
evidence
34
Replisomes
300
studies
42.4
evidence
35
Rna_complementary
300
studies
43.3
evidence
36
Thioflavin_t
300
studies
41.2
evidence
37
Exonucleases
300
studies
42.5
evidence
38
Isochores
300
studies
44.1
evidence
39
Suramin
300
studies
41.3
evidence
40
Tocotrienol
300
studies
40.3
evidence
41
Deoxyguanosine
300
studies
41.5
evidence
42
Epidermal_growth_factor
300
studies
46.2
evidence
43
Nucleic_acid_probes
300
studies
43.5
evidence
44
Peptide_nucleic_acids
300
studies
41.1
evidence
45
5_untranslated_regions
300
studies
43.6
evidence
46
Bleomycin
300
studies
41.7
evidence
47
Bortezomib
300
studies
48.3
evidence
48
Epigallocatechin3gallate
300
studies
37.9
evidence
49
F2_isoprostanes
300
studies
52.5
evidence
50
Keratin_19
300
studies
48.2
evidence
51
Mediator_complex
300
studies
44.6
evidence
52
Micrococcal_nuclease
300
studies
43.5
evidence
53
Oligodeoxyribonucleotides
300
studies
42.1
evidence
54
Oligonucleotides
300
studies
41.7
evidence
55
Omega6
300
studies
49.1
evidence
56
Phosphorothioate_oligonucleotides
300
studies
39.2
evidence
57
Rna_nuclear
300
studies
46.4
evidence
58
Rna_precursors
300
studies
43.9
evidence
59
Withaferin_a
300
studies
38.6
evidence
60
3_untranslated_regions
300
studies
44.4
evidence
61
Anthracenes
300
studies
40.4
evidence
62
Apolipoprotein_e4
300
studies
45.3
evidence
63
Apoprotein_a
300
studies
52.0
evidence
64
Autoantigens
300
studies
48.6
evidence
65
Biological_factors
300
studies
46.6
evidence
66
Camptothecin
300
studies
37.7
evidence
67
Chaperonins
300
studies
43.1
evidence
68
Cokecomplex mixture
300
studies
40.9
evidence
69
Corticosterone
300
studies
43.2
evidence
70
Crack_cocaine
300
studies
45.8
evidence
71
Crispr_associated_protein_9
300
studies
40.4
evidence
72
Dehydroepiandrosterone_sulfate
300
studies
51.4
evidence
73
Dideoxyadenosine
300
studies
40.7
evidence
74
Digoxigenin
300
studies
43.8
evidence
75
Diosgenin
300
studies
37.6
evidence
76
Dna_glycosylases
300
studies
38.5
evidence
77
Dna_ligases
300
studies
42.3
evidence
78
Dynactin_complex
300
studies
42.6
evidence
79
Etoposide
300
studies
46.2
evidence
80
Exoribonucleases
300
studies
44.6
evidence
81
Gammatocopherol
300
studies
47.5
evidence
82
Geldanamycin
300
studies
37.8
evidence
83
Glyceraldehyde_3_phosphate
300
studies
43.3
evidence
84
Hepatocyte_growth_factor
300
studies
46.0
evidence
85
Histone_deacetylase_1
300
studies
43.3
evidence
86
Keratin_14
300
studies
44.7
evidence
87
Ki_67_antigen
300
studies
50.6
evidence
88
Metalloporphyrins
300
studies
39.5
evidence
89
Morpholinosheterocyclic
300
studies
42.4
evidence
90
N_acetyl_cysteine
300
studies
45.6
evidence
91
Nandrolone_decanoate
300
studies
44.9
evidence
92
Novobiocin
300
studies
40.6
evidence
93
Oligonucleotide_probes
300
studies
44.1
evidence
94
Poly_a
300
studies
43.7
evidence
95
Poly_c
300
studies
41.4
evidence
96
Protein_phosphatase_1
300
studies
41.8
evidence
97
Sirtuin_1
300
studies
45.0
evidence
98
Stanozolol
300
studies
43.1
evidence
99
Terbium
300
studies
40.4
evidence
100
14_3_3_proteins
300
studies
43.4
evidence
101
8_hydroxy_2_deoxyguanosine
300
studies
48.6
evidence
102
Acrolein
300
studies
39.2
evidence
103
Adenosine_diphosphate_ribose
300
studies
46.3
evidence
104
Alphalinolenic_acid
300
studies
45.2
evidence
105
Angiopoietin_2
300
studies
52.6
evidence
106
Anthraquinones
300
studies
37.0
evidence
107
Apolipoproteins
300
studies
46.9
evidence
108
Bacillus_subtilis
300
studies
42.1
evidence
109
Beta_cyclodextrins
300
studies
38.6
evidence
110
Bromodeoxyuridine
300
studies
42.6
evidence
111
Celastrol
300
studies
37.9
evidence
112
Coffeecomplex mixture
300
studies
46.0
evidence
113
Colchicineheterocyclic
300
studies
46.1
evidence
114
Connective_tissue_growth_factor
300
studies
47.1
evidence
115
Cyclodextrins
300
studies
36.8
evidence
116
Cytosine_deaminase
300
studies
37.9
evidence
117
Deoxyribonucleotides
300
studies
41.9
evidence
118
Desmosomal_cadherins
300
studies
44.4
evidence
119
Dietary_sugars
300
studies
48.2
evidence
120
Dihydroorotase
300
studies
43.1
evidence
121
Diphosphates
300
studies
43.0
evidence
122
Dna_adducts
300
studies
39.5
evidence
123
Dna_complementary
300
studies
42.6
evidence
124
Dna_probes
300
studies
43.7
evidence
125
Dna_recombinant
300
studies
46.0
evidence
126
Doxorubicin
300
studies
41.6
evidence
127
Dyneins
300
studies
43.9
evidence
128
Endonucleases
300
studies
41.5
evidence
129
Epirubicin
300
studies
49.7
evidence
130
Epitopes
300
studies
43.5
evidence
131
Ethidium_bromide
300
studies
40.5
evidence
132
Ficoll
300
studies
43.0
evidence
133
Gemcitabine
300
studies
47.6
evidence
134
Ginseng_extract
300
studies
39.8
evidence
135
Growth_differentiation_factor_15
300
studies
54.9
evidence
136
Heparan_sulfate_proteoglycans
300
studies
43.6
evidence
137
Histone_deacetylase_3
300
studies
42.9
evidence
138
Histone_deacetylases
300
studies
42.6
evidence
139
Homocysteine
300
studies
44.8
evidence
140
Hygromycin_b
300
studies
41.6
evidence
141
Imatinib_mesylate
300
studies
46.3
evidence
142
Inositol_phosphates
300
studies
43.5
evidence
143
Interleukin_21
300
studies
46.2
evidence
144
Isoprostanes
300
studies
49.8
evidence
145
Keratin_1
300
studies
45.8
evidence
146
Keratin_10
300
studies
47.0
evidence
147
Keratin_17
300
studies
47.1
evidence
148
Keratin_18
300
studies
44.2
evidence
149
Keratin_5
300
studies
45.2
evidence
150
Keratin_8
300
studies
45.3
evidence
151
Macrocyclic_compounds
300
studies
37.9
evidence
152
Methoxypsoralen
300
studies
41.3
evidence
153
Micronutrients
300
studies
48.7
evidence
154
Micrornas
300
studies
47.2
evidence
155
Multienzyme_complexes
300
studies
41.7
evidence
156
Nandrolonepolycyclic
300
studies
42.4
evidence
157
Nanoconjugatespharmaceutical
300
studies
36.9
evidence
158
Nitroarginine
300
studies
40.0
evidence
159
Okadaic_acid
300
studies
35.7
evidence
160
Oridonin
300
studies
37.9
evidence
161
Oyster_mushroom
300
studies
40.6
evidence
162
Phospholipase_c_gamma
300
studies
43.3
evidence
163
Piperonyl_butoxide
300
studies
37.1
evidence
164
Platinum_nanoparticles
300
studies
36.3
evidence
165
Podoplanin
300
studies
49.7
evidence
166
Poly_adenosine_diphosphate_ribose
300
studies
46.8
evidence
167
Polycomb_group_proteins
300
studies
44.3
evidence
168
Porphyrins
300
studies
40.4
evidence
169
Proliferating_cell_nuclear_antigen
300
studies
45.0
evidence
170
Protein_phosphatase_2c
300
studies
42.7
evidence
171
Proteolipids
300
studies
43.4
evidence
172
Pseudouridine
300
studies
45.3
evidence
173
Pyrazoles
300
studies
41.4
evidence
174
Pyrroles
300
studies
43.6
evidence
175
Ribonuclease_h
300
studies
41.7
evidence
176
Rutin
300
studies
38.6
evidence
177
S_adenosylhomocysteine
300
studies
43.5
evidence
178
Sapogenins
300
studies
37.7
evidence
179
Sarcosine
300
studies
47.7
evidence
180
Sirtuins
300
studies
44.4
evidence
181
Stem_cell_factor
300
studies
43.5
evidence
182
Sulfites
300
studies
39.9
evidence
183
Tea
300
studies
39.9
evidence
184
Tert_butylhydroperoxide
300
studies
36.2
evidence
185
Tertbutyl_hydroperoxide
300
studies
35.9
evidence
186
Thymine_dna_glycosylase
300
studies
41.2
evidence
187
Vascular_endothelial_growth_factor_a
300
studies
48.0
evidence
188
Wortmannin
300
studies
39.1
evidence
189
Retroelements
299
studies
43.9
evidence
190
Guanine
299
studies
43.0
evidence
191
Perylene
299
studies
41.9
evidence
192
Streptonigrin
299
studies
37.1
evidence
193
Anthracyclines
299
studies
47.5
evidence
194
Arsenic
299
studies
38.7
evidence
195
Cholesterol_side_chain_cleavage_enzyme
299
studies
41.7
evidence
196
Thallium
299
studies
41.4
evidence
197
Arecoline
299
studies
39.4
evidence
198
Coal_tar
299
studies
40.4
evidence
199
Gtp_cyclohydrolase
299
studies
44.9
evidence
200
Hormone_antagonists
299
studies
44.0
evidence
201
Immunologic_factors
299
studies
46.7
evidence
202
Lipofuscin
299
studies
39.7
evidence
203
Neurturinpeptide
299
studies
45.6
evidence
204
Pepsinogens
299
studies
53.6
evidence
205
Protons
299
studies
42.5
evidence
206
Rank_ligand
299
studies
48.0
evidence
207
Rubidium
299
studies
42.7
evidence
208
Transcription_activator_like_effector_nucleases
299
studies
39.7
evidence
209
Urobilinogen
299
studies
44.7
evidence
210
Vidarabine
299
studies
47.5
evidence
211
Zinc_finger_nucleases
299
studies
39.7
evidence
212
Danazol
298
studies
46.6
evidence
213
Oxymetholone
298
studies
42.7
evidence
214
Mitoxantrone
298
studies
47.1
evidence
215
Arsenic_trioxide
298
studies
42.8
evidence
216
Biomarkers
298
studies
51.5
evidence
217
Clofarabinenucleotide
298
studies
51.0
evidence
218
Deferasirox
298
studies
52.8
evidence
219
Desmoglein_2
298
studies
49.2
evidence
220
Glucosylceramides
298
studies
44.7
evidence
221
Herpes_zoster_vaccine
298
studies
52.1
evidence
222
Vemurafenib
298
studies
50.7
evidence
223
Dideoxynucleosides
297
studies
39.8
evidence
224
Bisoprolol
297
studies
59.3
evidence
225
Epithelial_cell_adhesion_molecule
297
studies
45.1
evidence
226
Fluvastatin
297
studies
49.9
evidence
227
Leuprolide
297
studies
51.5
evidence
228
Rosiglitazone
297
studies
47.9
evidence
229
2deoxydglucose
296
studies
38.8
evidence
230
Deferoxamine
296
studies
43.3
evidence
231
Abacavir
295
studies
50.8
evidence
232
Milk_thistle
295
studies
41.7
evidence
233
Emtricitabine
292
studies
49.6
evidence
234
Ephrin_b1
291
studies
42.8
evidence
235
Acylphosphatase
273
studies
44.4
evidence
236
Endoribonucleases
273
studies
42.8
evidence
237
Agaricus_blazei
268
studies
39.1
evidence
238
Licochalcone_a
267
studies
38.6
evidence
239
Rna_antisense
266
studies
44.3
evidence
240
Gdf11
257
studies
43.1
evidence
241
Demecolcine
246
studies
39.9
evidence
242
Mitoq
191
studies
43.2
evidence
243
Natriuretic_peptide_brain
234
studies
51.8
evidence
244
Protoporphyrins
224
studies
40.4
evidence
245
Fructose_bisphosphatase
220
studies
44.6
evidence
246
Dna_mitochondrial
214
studies
44.9
evidence
247
Aporphines
210
studies
38.4
evidence
248
Apolipoprotein_e2
208
studies
51.9
evidence
249
Cucurbitacin_b
206
studies
37.5
evidence
250
Centromere_protein_a
200
studies
46.2
evidence
251
Methylene_blue
200
studies
41.6
evidence
252
Santalum_album
200
studies
40.6
evidence
253
Curcuma_longa
200
studies
33.0
evidence
254
Raphanus_sativus
200
studies
29.2
evidence
255
Fisetin
78
studies
45.3
evidence
256
Uroplakins
198
studies
44.7
evidence
257
Androgen_antagonists
186
studies
49.3
evidence
258
Cyclin_dependent_kinase_8
186
studies
41.3
evidence
259
Aurintricarboxylic_acid
184
studies
36.3
evidence
260
Chemokine_ccl21
184
studies
43.0
evidence
261
Dideoxynucleotides
183
studies
42.5
evidence
262
4_1bb_ligand
182
studies
40.2
evidence
263
Acridones
178
studies
36.7
evidence
264
Thymus_extracts
178
studies
44.5
evidence
265
Chondroitin_sulfate_proteoglycan_4
176
studies
42.1
evidence
266
Chemokine_ccl20
175
studies
47.7
evidence
267
Firefly_luciferin
173
studies
43.9
evidence
268
Hexadimethrine_bromide
172
studies
42.7
evidence
269
D_glucosamine
169
studies
49.6
evidence
270
Lewis_x_antigen
166
studies
47.8
evidence
271
Uroplakin_iii
164
studies
48.0
evidence
272
Fatty_acids_monounsaturated
162
studies
48.7
evidence
273
Cysteine_rich_protein_61
161
studies
48.2
evidence
274
Butein
158
studies
37.0
evidence
275
Vincristine_sulfate
158
studies
40.5
evidence
276
Keratin_13
156
studies
46.9
evidence
277
Mucin_5b
155
studies
51.7
evidence
278
Dna_single_stranded
151
studies
43.0
evidence
279
Nicotinamidaseenzyme
150
studies
42.1
evidence
280
Raw_cacao
138
studies
43.6
evidence
281
Adenomatous_polyposis_coli_protein
128
studies
44.8
evidence
282
Keratin_20
127
studies
49.2
evidence
283
Desonide
126
studies
49.5
evidence
284
Gloriosa_superba
126
studies
37.6
evidence
285
Keratin_9
122
studies
48.8
evidence
286
Lubricant_eye_drops
118
studies
53.9
evidence
287
Granulins
111
studies
43.8
evidence
288
Diflucortolone
106
studies
50.9
evidence
289
Fibroblast_growth_factor_3
106
studies
46.7
evidence
290
Ku_autoantigen
106
studies
43.6
evidence
291
Sb203580
106
studies
44.5
evidence
292
Wiskott_aldrich_syndrome_protein_family
106
studies
46.2
evidence
293
Centromere_protein_b
105
studies
46.0
evidence
294
Bombax_ceiba
105
studies
38.5
evidence
295
O_acetyl_adp_ribose
92
studies
42.9
evidence
296
Dna_satellite
90
studies
44.4
evidence
297
Antigens_cd34
87
studies
51.2
evidence
298
Aggrecans
81
studies
45.0
evidence
299
Hla_a2_antigen
80
studies
42.7
evidence
300
Werner_syndrome_helicase
73
studies
41.9
evidence
301
Dental_waste
62
studies
39.5
evidence
302
Dim
56
studies
39.9
evidence
303
Dna_circular
55
studies
40.5
evidence
304
Scriptaid
53
studies
36.0
evidence
305
Epitalon
48
studies
38.2
evidence
306
Dna_catalytic
46
studies
38.7
evidence
307
Rna_catalytic
44
studies
39.6
evidence
308
Dna_restriction_enzymes
40
studies
40.3
evidence
309
Hla_a3_antigen
29
studies
44.3
evidence
310
R2hydroxyglutarate
25
studies
41.0
evidence
311
Immobilized_nucleic_acids
20
studies
35.0
evidence
312
Angelica_sinensis_extract
12
studies
26.1
evidence

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