Question 1

What compounds affect the Aerobic respiration and respiratory electron transport pathway?

Accepted Answer

37 compounds in the BiohacksAI corpus have documented interactions with genes in the Aerobic respiration and respiratory electron transport pathway (Reactome ID: R-HSA-1428517). These compounds target 14 genes within this pathway.

Question 2

What genes are in the Aerobic respiration and respiratory electron transport pathway?

Accepted Answer

The Aerobic respiration and respiratory electron transport pathway involves 14 genes. Key genes include: COX1, COX2, DLD, FH, FXN, GLO1, MDH2, ND4, PDK1, PKLR.

#	Compound	Targets Hit	Studies
1	Suramin	—	300
2	fisetin	—	78
3	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
4	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
5	piceatannol	—	300
6	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
7	alphitonin [Supplementary Concept] from	—	300
8	Sirolimus	—	300
9	Spermidine	—	241
10	Catechin	—	300
11	Niclosamide	—	299
12	pd98059	—	7
13	Pseudoephedrine	—	298
14	Demeclocycline	—	5
15	Dinitrochlorobenzene	—	300
16	kenpaullone	—	8
17	Vorinostat	—	299
18	Disulfiram	—	297
19	Vanillic Acid	—	300
20	Aurintricarboxylic Acid	—	184
21	Cisplatin	—	300
22	Iodoacetamide	—	300
23	egcg	—	300
24	Rutin	—	300
25	Oxaprozin	—	181
26	Pioglitazone	—	297
27	streptonigrin	—	299
28	Quercetin	—	300
29	chrysin	—	300
30	Daunorubicin	—	298
31	Rotenone	—	300
32	19-((1'S,4'R)-4'-hydroxy-1'-methoxy-2'-oxopentyl)geldanamycin [Supplementary Concept]	—	300
33	triolimus [Supplementary Concept]	—	33
34	Doxycycline	—	999
35	Celecoxib	—	295
36	Glyburide	—	298
37	Sorafenib	—	300

BiohacksAI

Aerobic respiration and respiratory electron transport

Genes in this Pathway

Compounds Affecting Aerobic respiration and respiratory electron transport

About the Aerobic respiration and respiratory electron transport Pathway