Question 1

What compounds affect the Synthesis of PIPs at the plasma membrane pathway?

Accepted Answer

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Synthesis of PIPs at the plasma membrane pathway (Reactome ID: R-HSA-1660499). These compounds target 17 genes within this pathway.

Question 2

What genes are in the Synthesis of PIPs at the plasma membrane pathway?

Accepted Answer

The Synthesis of PIPs at the plasma membrane pathway involves 17 genes. Key genes include: BMX, INPPL1, PI4K2A, PI4K2B, PIK3C2A, PIK3C2B, PIK3C2G, PIK3CB, PIK3CD, PIK3CG.

#	Compound	Targets Hit	Studies
1	pictilisib	—	25
2	ly294002	—	11
3	Sirolimus	—	300
4	Wortmannin	—	300
5	torin 1	—	10
6	alpelisib	—	227
7	Crizotinib	—	298
8	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
9	piceatannol	—	300
10	Quercetin	—	300
11	Adenosine	—	298
12	Kaempferols	—	300
13	Thyroxine	—	994
14	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
15	Diiodotyrosine	—	300
16	Disulfiram	—	297
17	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
18	gamma-Linolenic Acid	—	300
19	Methyldopa	—	297
20	Masoprocol	—	300
21	Oxytetracycline	—	300
22	rafoxanide	—	172
23	Thyroxine	—	300
24	Ku 0063794 [Supplementary Concept]	—	7
25	Resveratrol	—	298
26	Aurintricarboxylic Acid	—	184
27	Gemfibrozil	—	297
28	Iodoacetamide	—	300
29	Chlorhexidine	—	299

BiohacksAI

Synthesis of PIPs at the plasma membrane

Genes in this Pathway

Compounds Affecting Synthesis of PIPs at the plasma membrane

About the Synthesis of PIPs at the plasma membrane Pathway