Question 1

What compounds affect the Plasma lipoprotein assembly, remodeling, and clearance pathway?

Accepted Answer

34 compounds in the BiohacksAI corpus have documented interactions with genes in the Plasma lipoprotein assembly, remodeling, and clearance pathway (Reactome ID: R-HSA-174824). These compounds target 9 genes within this pathway.

Question 2

What genes are in the Plasma lipoprotein assembly, remodeling, and clearance pathway?

Accepted Answer

The Plasma lipoprotein assembly, remodeling, and clearance pathway involves 9 genes. Key genes include: ALB, FURIN, NPC1, NR1H2, NR1H3, P4HB, PRKACA, PRKACB, PRKACG.

#	Compound	Targets Hit	Studies
1	hydroxyfasudil [Supplementary Concept]	—	11
2	Desmosterol	—	300
3	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
4	Warfarin	—	1,000
5	Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of	—	300
6	Tolbutamide	—	300
7	cbd	—	298
8	egcg	—	300
9	cannabidiol	—	296
10	Catechin	—	300
11	Evans Blue	—	300
12	Olmesartan Medoxomil	—	300
13	Phenylbutazone	—	300
14	Trazodone	—	297
15	Niclosamide	—	299
16	Pueraria	—	300
17	Genistein	—	300
18	Resveratrol	—	298
19	amlexanox	—	96
20	kenpaullone	—	8
21	pd98059	—	7
22	Riluzole	—	298
23	tyrphostin ag 1295	—	1
24	Hesperidin	—	300
25	Bosentan	—	298
26	piericidin	—	32
27	Progesterone	—	299
28	Gemfibrozil	—	297
29	alpelisib	—	227
30	Diminazene	—	300
31	silver sulfadiazine	—	299
32	juglone hydroxylase [Supplementary Concept] catalyzes	—	279
33	Equilin	—	216
34	Sphingosine	—	300

BiohacksAI

Plasma lipoprotein assembly, remodeling, and clearance

Genes in this Pathway

Compounds Affecting Plasma lipoprotein assembly, remodeling, and clearance

About the Plasma lipoprotein assembly, remodeling, and clearance Pathway