Question 1

What compounds affect the Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway?

Accepted Answer

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway (Reactome ID: R-HSA-2980767). These compounds target 7 genes within this pathway.

Question 2

What genes are in the Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway?

Accepted Answer

The Activation of NIMA Kinases NEK9, NEK6, NEK7 pathway involves 7 genes. Key genes include: CCNB1, CCNB2, CDK1, NEK6, NEK7, NEK9, PLK1.

#	Compound	Targets Hit	Studies
1	kenpaullone	—	8
2	alsterpaullone	—	12
3	indirubin	—	300
4	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
5	chrysin	—	300
6	fisetin	—	78
7	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
8	Quercetin	—	300
9	Crizotinib	—	298
10	Clofibrate	—	299
11	Fenofibrate	—	297
12	Sertraline	—	1,000
13	Cinnarizine	—	299
14	Clotrimazole	—	296
15	Rotenone	—	300
16	Sorafenib	—	300
17	sp600125	—	117
18	ly294002	—	11
19	Wortmannin	—	300
20	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
21	Oleic Acid	—	112
22	Simvastatin	—	1,000
23	cefaclor	—	299
24	Disulfiram	—	297
25	Hexachlorophene	—	300
26	Lithocholic Acid	—	300
27	Nisoldipine	—	297
28	Oxyphenbutazone	—	300
29	Oxytetracycline	—	300

BiohacksAI

Activation of NIMA Kinases NEK9, NEK6, NEK7

Genes in this Pathway

Compounds Affecting Activation of NIMA Kinases NEK9, NEK6, NEK7

About the Activation of NIMA Kinases NEK9, NEK6, NEK7 Pathway