Formyl peptide receptors bind formyl peptides and many other ligands

Q: What compounds affect the Formyl peptide receptors bind formyl peptides and many other ligands pathway?

36 compounds in the BiohacksAI corpus have documented interactions with genes in the Formyl peptide receptors bind formyl peptides and many other ligands pathway (Reactome ID: R-HSA-444473). These compounds target 4 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-4444734 genes36 compounds

The Formyl peptide receptors bind formyl peptides and many other ligands pathway (Reactome ID: R-HSA-444473) involves 4 genes and is affected by 36 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

APP FPR1 FPR2 FPR3

Compounds Affecting Formyl peptide receptors bind formyl peptides and many other ligands

#	Compound	Targets Hit	Studies
1	Perphenazine	—	297
2	Resveratrol	—	298
3	Quercetin	—	300
4	egcg	—	300
5	Hesperidin	—	300
6	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
7	Kaempferols	—	300
8	Methylene Blue	—	200
9	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
10	(N-methyl-C-11)-2-(4-methylamino-phenyl)-6-hydroxybenzothiazole [Supplementary Concept] neutral analog of amyloid-binding thioflavin-T (BTA) that crosses	—	300
11	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
12	caffeic acid	—	300
13	Vitamin	—	295
14	2-Methoxyestradiol	—	300
15	arctigenin-4-O-(3''-O-acetyl-beta-D-glucoside) [Supplementary Concept] isolated from	—	300
16	Cladribine	—	297
17	Digitoxin	—	300
18	Digoxin	—	299
19	Disulfiram	—	297
20	Edetic Acid	—	24
21	Catechin	—	300
22	Vanillic Acid	—	300
23	Ouabain	—	300
24	Podophyllotoxin	—	14
25	Quinic Acid	—	218
26	Retinaldehyde	—	300
27	streptonigrin	—	299
28	Trifluridine	—	295
29	Phenylbutazone	—	300
30	Sulfinpyrazone	—	300
31	Chenodeoxycholic Acid	—	299
32	Deoxycholic Acid	—	300
33	Monoiodotyrosine	—	274
34	Masoprocol	—	300
35	Ticagrelor	—	299
36	Adenosine Triphosphate	—	300

About the Formyl peptide receptors bind formyl peptides and many other ligands Pathway

The Formyl peptide receptors bind formyl peptides and many other ligands pathway is catalogued in Reactome (ID: R-HSA-444473) and involves 4 genes. In the BiohacksAI corpus, 36 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include APP, FPR1, FPR2, FPR3.