What genes are in the Respiratory syncytial virus genome replication pathway?

The Respiratory syncytial virus genome replication pathway involves 2 genes. Key genes include: HSP90AA1, HSP90AB1.

Respiratory syncytial virus genome replication

Q: What compounds affect the Respiratory syncytial virus genome replication pathway?

30 compounds in the BiohacksAI corpus have documented interactions with genes in the Respiratory syncytial virus genome replication pathway (Reactome ID: R-HSA-9834752). These compounds target 2 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-98347522 genes30 compounds

The Respiratory syncytial virus genome replication pathway (Reactome ID: R-HSA-9834752) involves 2 genes and is affected by 30 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

HSP90AA1 HSP90AB1

Compounds Affecting Respiratory syncytial virus genome replication

#	Compound	Targets Hit	Studies
1	19-((1'S,4'R)-4'-hydroxy-1'-methoxy-2'-oxopentyl)geldanamycin [Supplementary Concept]	—	300
2	triolimus [Supplementary Concept]	—	33
3	monorden	—	8
4	gedunin	—	54
5	celastrol	—	300
6	Novobiocin	—	300
7	caffeic acid	—	300
8	Masoprocol	—	300
9	Tetracycline	—	300
10	Zearalenone (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradec in-1,7(8H)-dione.	—	300
11	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
12	Quercetin	—	300
13	ag490	—	14
14	Idarubicin	—	299
15	piceatannol	—	300
16	Nitroprusside	—	299
17	2-Chloroadenosine 2-Chloroadenosine.	—	300
18	Adenylyl Imidodiphosphate 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid.	—	300
19	Calcimycin	—	216
20	Calcitriol	—	300
21	Ciclopirox	—	88
22	Clotrimazole	—	296
23	cycloheximide	—	300
24	deguelin [Supplementary Concept]	—	151
25	Disulfiram	—	297
26	Hexachlorophene	—	300
27	Indazoles	—	300
28	Miconazole	—	298
29	specioside	—	6
30	Wortmannin	—	300

About the Respiratory syncytial virus genome replication Pathway

The Respiratory syncytial virus genome replication pathway is catalogued in Reactome (ID: R-HSA-9834752) and involves 2 genes. In the BiohacksAI corpus, 30 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HSP90AA1, HSP90AB1.