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BiohacksAI/Compounds/Sitagliptin/Similar

Compounds Similar to Sitagliptin

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Sitagliptin, including interactions with DPP4, CHAIN, 5-HYDROXYTRYPTAMINE. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Sitagliptin profile →INSULIN SIGNALING pathwayGLUCOSE METABOLISM pathway
Similar Compounds — Ranked by Target Overlap
1
saxagliptin
3
shared
37%
overlap
2
bdb
3
shared
13
studies
37%
overlap
3
bdb
3
shared
5
studies
37%
overlap
4
vildagliptin
3
shared
32%
overlap
5
linagliptin
3
shared
30%
overlap
6
bdb
2
shared
2
studies
26%
overlap
7
Sitagliptin
2
shared
85
studies
24%
overlap
8
diprotin
2
shared
23%
overlap
9
talabostat
3
shared
22%
overlap
10
bdb
2
shared
2
studies
20%
overlap
Shared Biological Targets
DPP4CHAIN5-HYDROXYTRYPTAMINEDIPEPTIDYLDPP8

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Sitagliptin full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.