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Compounds Similar to Sorafenib

10 compounds with shared biological targets · BiohacksAI corpus current

The compounds below share molecular targets and biological mechanisms with Sorafenib, including interactions with BRAF, ABL1, AURKB. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
foretinib
105
shared
37%
overlap
2
ast
106
shared
34%
overlap
3
doramapimod
70
shared
31%
overlap
4
rebastinib
71
shared
29%
overlap
5
vandetanib
69
shared
28%
overlap
69
shared
298
studies
27%
overlap
85
shared
298
studies
27%
overlap
8
quizartinib
57
shared
27%
overlap
9
linifanib
62
shared
26%
overlap
10
fedratinib
100
shared
25%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Sorafenib full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.