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Chlorpheniramine

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.

298+ PubMed studies analyzed · 46 RCTs · Evidence Score: 47

Research Domains

Chlorpheniramine has been studied across 17 research domains including 🧠 Focus & Attention, 😴 Sleep, 🫁 Respiratory, 🌤️ Mood & Depression, 💊 Pain. The primary research focus is 🧠 Focus & Attention with 9% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Chlorpheniramine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

protriptyline
13 shared targets
desloratadine
10 shared targets
methapyrilene
9 shared targets
Nefopam
9 shared targets
orphenadrine
10 shared targets
dexchlorpheniramine
9 shared targets
Hydroxyzine
13 shared targets
Cetirizine
7 shared targets
doxepin
9 shared targets
clomipramine
10 shared targets
Loading evidence profile...

This evidence profile for Chlorpheniramine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.