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Mefruside

A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level.

75+ PubMed studies analyzed · 10 RCTs · Evidence Score: 45.4

Research Domains

Mefruside has been studied across 13 research domains including ❤️ Cardiovascular, 🫘 Kidney, 🧠 Focus & Attention, 🔥 Metabolic, 🫁 Liver & Detox. The primary research focus is ❤️ Cardiovascular with 64% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Mefruside, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Aminopyrine
2 shared targets
Darunavir
2 shared targets
Doripenem
2 shared targets
Dexamethasone
2 shared targets
Abacavir
2 shared targets
propyl
2 shared targets
Flumethasone
2 shared targets
Prednisone
2 shared targets
Dimethisterone
2 shared targets
Pregnenolone
2 shared targets
Loading evidence profile...

This evidence profile for Mefruside is generated deterministically from 75 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.