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Mescaline

the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.

300+ PubMed studies analyzed · 3 RCTs · Evidence Score: 42.2

Research Domains

Mescaline has been studied across 15 research domains including 🌤️ Mood & Depression, 🧠 Focus & Attention, 🧠 Learning, 🫁 Liver & Detox, 😴 Sleep. The primary research focus is 🌤️ Mood & Depression with 12% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Mescaline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Sumatriptan
13 shared targets
serotonin
11 shared targets
brl
9 shared targets
Pergolide
17 shared targets
Quipazine
12 shared targets
psilocin
10 shared targets
5
8 shared targets
Bufotenin
11 shared targets
ketanserin
9 shared targets
brexpiprazole
13 shared targets
Loading evidence profile...

This evidence profile for Mescaline is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.