BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Pergolide

A long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.

299+ PubMed studies analyzed · 39 RCTs · Evidence Score: 49.4

Research Domains

Pergolide has been studied across 22 research domains including 🌤️ Mood & Depression, 🧠 Focus & Attention, 🧠 Neuroprotection, 😴 Sleep, ❤️ Cardiovascular. The primary research focus is 🌤️ Mood & Depression with 62% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Pergolide, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Lisuride
28 shared targets
Yohimbine
28 shared targets
Ergotamine
25 shared targets
Dihydroergotamine
28 shared targets
Quetiapine
29 shared targets
Oxymetazoline
21 shared targets
Trazodone
23 shared targets
Mianserin
31 shared targets
Cyproheptadine
32 shared targets
risperidone
23 shared targets
Loading evidence profile...

This evidence profile for Pergolide is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.