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Modafinil

A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.

297+ PubMed studies analyzed · 58 RCTs · Evidence Score: 51.2

Research Domains

Modafinil has been studied across 17 research domains including 😴 Sleep, 🧠 Focus & Attention, 🧠 Cognitive, 🌤️ Mood & Depression, ⚡ Energy & Fatigue. The primary research focus is 😴 Sleep with 28% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Modafinil, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Aztreonam
4 shared targets
Pinacidil
4 shared targets
Midodrine
4 shared targets
Venlafaxine
3 shared targets
Metaraminol
4 shared targets
Sulfadoxine
4 shared targets
Felbamate
4 shared targets
idebenone
3 shared targets
Reboxetine
2 shared targets
Nateglinide
4 shared targets
Loading evidence profile...

This evidence profile for Modafinil is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.