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Pinacidil

A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)

300+ PubMed studies analyzed · 19 RCTs · Evidence Score: 44.9

Research Domains

Pinacidil has been studied across 19 research domains including ❤️ Cardiovascular, ⚡ Energy & Fatigue, 🦴 Bone & Joint, 🔥 Metabolic, 🧠 Focus & Attention. The primary research focus is ❤️ Cardiovascular with 36% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Pinacidil, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Aztreonam
4 shared targets
idebenone
4 shared targets
Midodrine
4 shared targets
Dexamethasone
5 shared targets
Metaraminol
4 shared targets
Torsemide
5 shared targets
Modafinil
4 shared targets
Sulfaphenazole
5 shared targets
Sulfadoxine
4 shared targets
Felbamate
4 shared targets
Loading evidence profile...

This evidence profile for Pinacidil is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.