A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Nicorandil has been studied across 22 research domains including ❤️ Cardiovascular, ⚡ Energy & Fatigue, 🔬 Inflammation, 🔬 Oncology, 🧘 Stress & Anxiety. The primary research focus is ❤️ Cardiovascular with 43% of studies addressing this area.
The following compounds share molecular targets with Nicorandil, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Nicorandil is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.