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Ryanodine

A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.

299+ PubMed studies analyzed · Evidence Score: 42.3

Research Domains

Ryanodine has been studied across 17 research domains including 🦴 Bone & Joint, 🏋️ Muscle & Hypertrophy, 🔥 Metabolic, ❤️ Cardiovascular, 🧠 Focus & Attention. The primary research focus is 🦴 Bone & Joint with 96% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Ryanodine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Dantrolene
3 shared targets
Caffeine
3 shared targets
Adenosine
3 shared targets
Suramin
2 shared targets
dendrobium
2 shared targets
curculigo
2 shared targets
scolopendra
2 shared targets
atractylodes
2 shared targets
agastache
2 shared targets
Raphanus
2 shared targets
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This evidence profile for Ryanodine is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.