A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.
Vortioxetine has been studied across 16 research domains including 🌤️ Mood & Depression, 🧠 Cognitive, 🧘 Stress & Anxiety, 🧠 Memory, 🧠 Focus & Attention. The primary research focus is 🌤️ Mood & Depression with 48% of studies addressing this area.
The following compounds share molecular targets with Vortioxetine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Vortioxetine is generated deterministically from 294 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.