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BiohacksAI/Targets/CDK8
MOLECULAR TARGET

CDK8

cyclin dependent kinase 8

134 compounds · BiohacksAI corpus v20260307-01

134
compounds
Compounds
134
Gene Symbol
CDK8
NCBI Gene
1024

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About CDK8

CDK8 (cyclin dependent kinase 8) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 134 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting CDK8 (50)
1
Alvocidib
4.52
confidence
2
Foretinib
4.34
confidence
3
Ponatinib
4.26
confidence
4
Doramapimod
4.06
confidence
5
Quizartinib
3.99
confidence
6
Dinaciclib
3.87
confidence
7
Vatalanib
3.69
confidence
8
Tpck
3.47
confidence
9
Bms 387032
3.47
confidence
10
Linifanib
3.33
confidence
11
Lestaurtinib
3.04
confidence
12
Plx 4720
2.71
confidence
13
Cp 724714
2.56
confidence
14
Ast 487
2.56
confidence
15
Ct 7001
2.20
confidence
16
Sel 120 Free Base
1.95
confidence
17
Voruciclib
1.79
confidence
18
Sorafenib
300
studies
1.39
confidence
19
Ha1077
11
studies
1.10
confidence
20
Paeonia Lactiflora
1.00
confidence
21
Morus Alba
1.00
confidence
22
Nelumbo Nucifera
0
studies
1.00
confidence
23
Agastache Rugosa
1.00
confidence
24
Allium Sativum
500
studies
1.00
confidence
25
Allium Tuberosum
1.00
confidence
26
Aloe Vera
1.00
confidence
27
Arctium Lappa
1.00
confidence
28
Artemisia Capillaris
1.00
confidence
29
Aster Tataricus
1.00
confidence
30
Bupleurum Chinense
1.00
confidence
31
Carthamus Tinctorius
1.00
confidence
32
Centella Asiatica
499
studies
1.00
confidence
33
Chaenomeles Speciosa
1.00
confidence
34
Citrus Reticulata
1.00
confidence
35
Crataegus Pinnatifida
1.00
confidence
36
Curcuma Longa
500
studies
1.00
confidence
37
Cynomorium Songaricum
1.00
confidence
38
Ephedra Sinica
1.00
confidence
39
Eriobotrya Japonica
1.00
confidence
40
Eucommia Ulmoides
1.00
confidence
41
Forsythia Suspensa
1.00
confidence
42
Fritillaria Cirrhosa
1.00
confidence
43
Gastrodia Elata
1.00
confidence
44
Ginkgo Biloba
299
studies
1.00
confidence
45
Glycyrrhiza Uralensis
1.00
confidence
46
Lilium Lancifolium
1.00
confidence
47
Litchi Chinensis
1.00
confidence
48
Lithospermum Erythrorhizon
1.00
confidence
49
Lobelia Chinensis
1.00
confidence
50
Lonicera Japonica
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.