MOLECULAR TARGETUniProt: P22734
COMT
catechol-O-methyltransferase
125 compounds · BiohacksAI corpus v20260307-01
125
compounds
Compounds
125
Gene Symbol
COMT
NCBI Gene
24267
Looking for compounds that interact with COMT?
View all 125 compounds →About COMT
COMT (catechol-O-methyltransferase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 125 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.
View COMT on UniProt →Compounds Targeting COMT (50)
1
Oxyquinoline
3.85
confidence
2
Tolcapone
3.76
confidence
3
Entacapone
3.43
confidence
300
studies
1.10
confidence
5
Achyranthes Bidentata
1.00
confidence
6
Aconitum Carmichaelii
1.00
confidence
7
Agastache Rugosa
1.00
confidence
500
studies
1.00
confidence
9
Aloe Vera
1.00
confidence
10
Arctium Lappa
1.00
confidence
199
studies
1.00
confidence
12
Artemisia Annua
1.00
confidence
13
Artemisia Argyi
1.00
confidence
14
Artemisia Capillaris
1.00
confidence
15
Atractylodes Macrocephala
1.00
confidence
16
Bufo Bufo
1.00
confidence
17
Bupleurum Chinense
1.00
confidence
18
Carthamus Tinctorius
1.00
confidence
499
studies
1.00
confidence
20
Chaenomeles Speciosa
1.00
confidence
21
Cimicifuga Heracleifolia
1.00
confidence
22
Citrus Reticulata
1.00
confidence
23
Crataegus Pinnatifida
1.00
confidence
500
studies
1.00
confidence
25
Cuscuta Chinensis
1.00
confidence
26
Cynomorium Songaricum
1.00
confidence
27
Dimocarpus Longan
1.00
confidence
28
Ephedra Sinica
1.00
confidence
29
Eriobotrya Japonica
1.00
confidence
30
Eucommia Ulmoides
1.00
confidence
499
studies
1.00
confidence
32
Forsythia Suspensa
1.00
confidence
33
Fritillaria Cirrhosa
1.00
confidence
34
Gastrodia Elata
1.00
confidence
299
studies
1.00
confidence
36
Glycine Max
1.00
confidence
37
Glycyrrhiza Uralensis
1.00
confidence
38
Inula Japonica
1.00
confidence
39
Ligusticum Chuanxiong
1.00
confidence
40
Lilium Lancifolium
1.00
confidence
41
Litchi Chinensis
1.00
confidence
42
Lithospermum Erythrorhizon
1.00
confidence
43
Lobelia Chinensis
1.00
confidence
44
Lonicera Japonica
1.00
confidence
45
Mentha Haplocalyx
1.00
confidence
46
Morus Alba
1.00
confidence
0
studies
1.00
confidence
48
Paeonia Lactiflora
1.00
confidence
300
studies
1.00
confidence
50
Panax Notoginseng
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed
All data is computationally derived from published research. Not medical advice. Independent validation required.