BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/DOT1L
MOLECULAR TARGETUniProt: Q8TEK3

DOT1L

DOT1 like histone lysine methyltransferase

88 compounds · BiohacksAI corpus v20260307-01

88
compounds
Compounds
88
Gene Symbol
DOT1L
NCBI Gene
84444

Looking for compounds that interact with DOT1L?

View all 88 compounds →
About DOT1L

DOT1L (DOT1 like histone lysine methyltransferase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 88 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View DOT1L on UniProt →
Compounds Targeting DOT1L (50)
1
Sinefungin
3.74
confidence
2
Iodotubercidin
3.30
confidence
3
Sangivamycin
3.00
confidence
4
S Adenosylhomocysteine
300
studies
2.40
confidence
5
Agastache Rugosa
1.00
confidence
6
Allium Sativum
500
studies
1.00
confidence
7
Artemisia Annua
1.00
confidence
8
Artemisia Argyi
1.00
confidence
9
Artemisia Capillaris
1.00
confidence
10
Atractylodes Macrocephala
1.00
confidence
11
Bupleurum Chinense
1.00
confidence
12
Centella Asiatica
499
studies
1.00
confidence
13
Citrus Reticulata
1.00
confidence
14
Cnidium Monnieri
1.00
confidence
15
Curcuma Longa
500
studies
1.00
confidence
16
Eriobotrya Japonica
1.00
confidence
17
Eucommia Ulmoides
1.00
confidence
18
Foeniculum Vulgare
499
studies
1.00
confidence
19
Ginkgo Biloba
299
studies
1.00
confidence
20
Ligusticum Chuanxiong
1.00
confidence
21
Litchi Chinensis
1.00
confidence
22
Lonicera Japonica
1.00
confidence
23
Mosla Chinensis
1.00
confidence
24
Nelumbo Nucifera
0
studies
1.00
confidence
25
Panax Ginseng
300
studies
1.00
confidence
26
Panax Notoginseng
1.00
confidence
27
Perilla Frutescens
1.00
confidence
28
Pinellia Ternata
1.00
confidence
29
Piper Nigrum
0
studies
1.00
confidence
30
Portulaca Oleracea
500
studies
1.00
confidence
31
Prunus Mume
1.00
confidence
32
Schisandra Chinensis
1.00
confidence
33
Taxillus Chinensis
1.00
confidence
34
Zingiber Officinale
498
studies
1.00
confidence
35
Ziziphus Jujuba
1.00
confidence
36
Cyproheptadine
299
studies
0.69
confidence
37
Achyranthes Bidentata
0.50
confidence
38
Aconitum Carmichaelii
0.50
confidence
39
Allium Fistulosum
0.50
confidence
40
Allium Tuberosum
0.50
confidence
41
Aloe Vera
0.50
confidence
42
Anemarrhena Asphodeloides
0.50
confidence
43
Apis Mellifera
0.50
confidence
44
Aquilaria Sinensis
0.50
confidence
45
Arctium Lappa
0.50
confidence
46
Areca Catechu
199
studies
0.50
confidence
47
Aucklandia Lappa
0.50
confidence
48
Carthamus Tinctorius
0.50
confidence
49
Chaenomeles Speciosa
0.50
confidence
50
Coix Lacryma
0.50
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.