BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGETUniProt: P28335

HTR2C

5-hydroxytryptamine receptor 2C

280 compounds · BiohacksAI corpus v20260307-01

280
compounds
Compounds
280
Gene Symbol
HTR2C
NCBI Gene
3358

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About HTR2C

HTR2C (5-hydroxytryptamine receptor 2C) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 280 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View HTR2C on UniProt →
Compounds Targeting HTR2C (50)
1
Tamoxifen
5.88
confidence
2
Clozapine
5.81
confidence
3
Imipramine
5.69
confidence
4
Serotonin
5.47
confidence
5
Nifedipine
5.34
confidence
6
8 Oh Dpat
4.98
confidence
7
Risperidone
4.89
confidence
8
Ketanserin
4.85
confidence
9
Ly 294002
4.84
confidence
10
Raloxifene
4.77
confidence
11
Terfenadine
4.55
confidence
12
Propafenone
4.53
confidence
13
Thioridazine
4.52
confidence
14
Amiodarone
4.51
confidence
15
Olanzapine
4.44
confidence
16
Citalopram
4.36
confidence
17
Clomipramine
4.28
confidence
18
Spiperone
4.23
confidence
19
Diphenhydramine
4.22
confidence
20
Promazine
4.19
confidence
21
Pyrilamine
4.17
confidence
22
Diethylstilbestrol
4.06
confidence
23
Propofol
4.01
confidence
24
Ib Meca
4.01
confidence
25
Ziprasidone
3.99
confidence
26
Namodenoson
3.95
confidence
27
Fluphenazine
3.91
confidence
28
Salmeterol
3.76
confidence
29
Amentoflavone
3.76
confidence
30
Ritanserin
3.61
confidence
31
Lysergide
3.61
confidence
32
Sertindole
3.58
confidence
33
Tryptamine
3.56
confidence
34
Doxazosin
3.53
confidence
35
Doxepin
3.50
confidence
36
Ketotifen
3.47
confidence
37
Mirtazapine
3.43
confidence
38
Chlorophenylpiperazine
3.37
confidence
39
Prochlorperazine
3.33
confidence
40
Mebufotenin
3.33
confidence
41
Agomelatine
3.33
confidence
42
Droperidol
3.30
confidence
43
Desloratadine
3.26
confidence
44
Azelastine
3.26
confidence
45
5 Methoxytryptamine
3.18
confidence
46
Purvalanola
3.18
confidence
47
Mesulergine
3.18
confidence
48
Phenothiazine
3.14
confidence
298
studies
3.04
confidence
299
studies
3.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.