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BiohacksAI/Targets/NLRP3
MOLECULAR TARGETUniProt: AAI43360

NLRP3

NLR family pyrin domain containing 3

136 compounds · BiohacksAI corpus v20260307-01

136
compounds
Compounds
136
Gene Symbol
NLRP3
NCBI Gene
114548

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About NLRP3

NLRP3 (NLR family pyrin domain containing 3) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 136 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View NLRP3 on UniProt →
Compounds Targeting NLRP3 (50)
1
Isoliquiritigenin
4.50
confidence
2
Micheliolide
2.08
confidence
3
Niclosamideorganic
0
studies
1.61
confidence
4
Lithocholic Acid
300
studies
1.61
confidence
5
Hexachlorophene
300
studies
1.61
confidence
6
Androsterone
300
studies
1.61
confidence
7
Cycloheximide
300
studies
1.61
confidence
8
Etiocholanolone
300
studies
1.61
confidence
9
Dimethyl Fumarate
296
studies
1.61
confidence
10
Tyrphostin 9
2
studies
1.61
confidence
11
Thioridazine Hydrochloride
35
studies
1.39
confidence
12
Calcitriol
300
studies
1.39
confidence
13
Dihydrotestosterone
300
studies
1.39
confidence
14
Ethinyl Estradiol
300
studies
1.39
confidence
15
Oridonin
300
studies
1.10
confidence
16
20 Alpha Dihydroprogesterone
224
studies
1.10
confidence
17
Anisomycin
247
studies
1.10
confidence
18
Chlorhexidine
299
studies
1.10
confidence
19
Tocainide
299
studies
1.10
confidence
20
Panax Ginseng
300
studies
1.00
confidence
21
Litchi Chinensis
1.00
confidence
22
Lobelia Chinensis
1.00
confidence
23
Lonicera Japonica
1.00
confidence
24
Nelumbo Nucifera
0
studies
1.00
confidence
25
Agastache Rugosa
1.00
confidence
26
Allium Tuberosum
1.00
confidence
27
Aloe Vera
1.00
confidence
28
Anemarrhena Asphodeloides
1.00
confidence
29
Artemisia Argyi
1.00
confidence
30
Artemisia Capillaris
1.00
confidence
31
Aster Tataricus
1.00
confidence
32
Atractylodes Macrocephala
1.00
confidence
33
Bupleurum Chinense
1.00
confidence
34
Carthamus Tinctorius
1.00
confidence
35
Centella Asiatica
499
studies
1.00
confidence
36
Chaenomeles Speciosa
1.00
confidence
37
Citrus Reticulata
1.00
confidence
38
Curcuma Longa
500
studies
1.00
confidence
39
Cuscuta Chinensis
1.00
confidence
40
Cynomorium Songaricum
1.00
confidence
41
Dimocarpus Longan
1.00
confidence
42
Ephedra Sinica
1.00
confidence
43
Epimedium Brevicornum
1.00
confidence
44
Eriobotrya Japonica
1.00
confidence
45
Eucommia Ulmoides
1.00
confidence
46
Fritillaria Cirrhosa
1.00
confidence
47
Ginkgo Biloba
299
studies
1.00
confidence
48
Glycine Max
1.00
confidence
49
Glycyrrhiza Uralensis
1.00
confidence
50
Ligusticum Chuanxiong
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.