BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/POLB
MOLECULAR TARGETUniProt: P06746

POLB

DNA polymerase beta

151 compounds · BiohacksAI corpus v20260307-01

151
compounds
Compounds
151
Gene Symbol
POLB
NCBI Gene
5423

Looking for compounds that interact with POLB?

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About POLB

POLB (DNA polymerase beta) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 151 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View POLB on UniProt →
Compounds Targeting POLB (50)
1
Betulinic Acid
5.21
confidence
2
Beta Sitosterol
3.95
confidence
3
Corosolic Acid
3.40
confidence
4
Zidovudine Triphosphate
3.18
confidence
5
Ilimaquinone
2.71
confidence
6
Pamoic Acid
2.30
confidence
7
Stigmasterol
300
studies
1.95
confidence
8
Oleanolic Acid
300
studies
1.95
confidence
9
Protocatechuic Acid
300
studies
1.61
confidence
10
Methyldopa
297
studies
1.10
confidence
11
Ursolic Acid
300
studies
1.10
confidence
12
Smilax Glabra
1.00
confidence
13
Syzygium Aromaticum
500
studies
1.00
confidence
14
Verbena Officinalis
1.00
confidence
15
Ziziphus Jujuba
1.00
confidence
16
Achyranthes Bidentata
1.00
confidence
17
Agastache Rugosa
1.00
confidence
18
Allium Sativum
500
studies
1.00
confidence
19
Centella Asiatica
499
studies
1.00
confidence
20
Chaenomeles Speciosa
1.00
confidence
21
Crataegus Pinnatifida
1.00
confidence
22
Eriobotrya Japonica
1.00
confidence
23
Eucommia Ulmoides
1.00
confidence
24
Foeniculum Vulgare
499
studies
1.00
confidence
25
Forsythia Suspensa
1.00
confidence
26
Gentiana Macrophylla
1.00
confidence
27
Glycyrrhiza Uralensis
1.00
confidence
28
Lithospermum Erythrorhizon
1.00
confidence
29
Nelumbo Nucifera
0
studies
1.00
confidence
30
Morus Alba
1.00
confidence
31
Panax Ginseng
300
studies
1.00
confidence
32
Panax Notoginseng
1.00
confidence
33
Perilla Frutescens
1.00
confidence
34
Platycodon Grandiflorus
1.00
confidence
35
Prunella Vulgaris
1.00
confidence
36
Rubia Cordifolia
200
studies
1.00
confidence
37
Salvia Miltiorrhiza
1.00
confidence
38
Schisandra Chinensis
1.00
confidence
39
Scutellaria Baicalensis
1.00
confidence
40
Smilax China
142
studies
1.00
confidence
41
Amethopterin
289
studies
0.69
confidence
42
Calycosin
300
studies
0.69
confidence
43
Demeclocycline Hydrochloride
5
studies
0.69
confidence
44
Dequalinium Chloride
46
studies
0.69
confidence
45
Emodin
300
studies
0.69
confidence
46
Hexachlorophene
300
studies
0.69
confidence
47
Idarubicin
299
studies
0.69
confidence
48
Oxytetracycline
300
studies
0.69
confidence
49
Piceatannoldrugage
0
studies
0.69
confidence
50
Sodium Nitroprusside
299
studies
0.69
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.