What compounds target EHMT1?

BiohacksAI has identified 88 compounds that interact with EHMT1 (euchromatic histone lysine methyltransferase 1). Top compounds include: ebselen, sinefungin, naphthoquinone, ditiocarb sodium, thiram. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is EHMT1 (euchromatic histone lysine)?

EHMT1 is euchromatic histone lysine methyltransferase 1. It is a molecular target for 88 compounds documented in PubMed bioassay data. UniProt ID: Q9H9B1. NCBI Gene ID: 79813.

EHMT1

MOLECULAR TARGET

euchromatic histone lysine methyltransferase 1

UniProt: Q9H9B1 NCBI Gene: 7981388 compounds

EHMT1 (euchromatic histone lysine methyltransferase 1) is targeted by 88 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting EHMT1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	ebselen	4.74	113
2	sinefungin	3.74	41
3	naphthoquinone	3.58	35
4	ditiocarb sodium	3.53	33
5	thiram	2.48	11
6	Disulfiram	1.95	6
7	benzene selenoic acid	1.79	5
8	agastache rugosa	1.00	1
9	Garlic	1.00	1
10	aloe vera	1.00	1
11	arctium lappa	1.00	1
12	artemisia argyi	1.00	1
13	artemisia capillaris	1.00	1
14	atractylodes macrocephala	1.00	1
15	Centella	1.00	1
16	chaenomeles speciosa	1.00	1
17	citrus reticulata	1.00	1
18	crataegus pinnatifida	1.00	1
19	Curcuma	1.00	1
20	eupatorium fortunei	1.00	1
21	forsythia suspensa	1.00	1
22	Ginkgo biloba	1.00	1
23	glycine max	1.00	1
24	lonicera japonica	1.00	1
25	magnolia biondii	1.00	1
26	morus alba	1.00	1
27	Nelumbo	1.00	1
28	Panax	1.00	1
29	panax notoginseng	1.00	1
30	perilla frutescens	1.00	1
31	pinellia ternata	1.00	1
32	polygonum cuspidatum	1.00	1
33	Portulaca	1.00	1
34	prunus armeniaca	1.00	1
35	prunus mume	1.00	1
36	Rubia	1.00	1
37	schisandra chinensis	1.00	1
38	scutellaria baicalensis	1.00	1
39	smilax glabra	1.00	1
40	taxillus chinensis	1.00	1
41	vigna umbellata	1.00	1
42	Zingiber officinale Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as	1.00	1
43	Glutathione	0.69	1
44	Anthraquinones Compounds based on ANTHRACENES which contain two KETONES in	0.69	1
45	Dimethyl Sulfoxide	0.69	1
46	ninhydrin	0.69	1
47	s adenosylhomocysteine	0.69	1
48	achyranthes bidentata	0.50	1
49	aconitum carmichaelii	0.50	1
50	apis mellifera	0.50	1

Showing top 50 of 88 compounds. Use the BiohacksAI search to explore all EHMT1 modulators.

About EHMT1 as a Drug Target

EHMT1 (euchromatic histone lysine methyltransferase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 88 compounds with documented EHMT1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

EHMT1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.