What compounds target NAMPT?

BiohacksAI has identified 106 compounds that interact with NAMPT (Nicotinamide phosphoribosyltransferase). Top compounds include: tucidinostat, achyranthes bidentata, agastache rugosa, Garlic, aloe vera. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is NAMPT (Nicotinamide phosphoribosyltransferase)?

NAMPT is Nicotinamide phosphoribosyltransferase. It is a molecular target for 106 compounds documented in PubMed bioassay data.

NAMPT

MOLECULAR TARGET

Nicotinamide phosphoribosyltransferase

106 compounds

NAMPT (Nicotinamide phosphoribosyltransferase) is targeted by 106 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting NAMPT

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	tucidinostat	3.04	20
2	achyranthes bidentata	1.00	1
3	agastache rugosa	1.00	1
4	Garlic	1.00	1
5	aloe vera	1.00	1
6	anemarrhena asphodeloides	1.00	1
7	arctium lappa	1.00	1
8	artemisia argyi	1.00	1
9	artemisia capillaris	1.00	1
10	Centella	1.00	1
11	chaenomeles speciosa	1.00	1
12	citrus reticulata	1.00	1
13	crataegus pinnatifida	1.00	1
14	Curcuma	1.00	1
15	cynomorium songaricum	1.00	1
16	ephedra sinica	1.00	1
17	eriobotrya japonica	1.00	1
18	eucommia ulmoides	1.00	1
19	Foeniculum	1.00	1
20	forsythia suspensa	1.00	1
21	fritillaria cirrhosa	1.00	1
22	gentiana macrophylla	1.00	1
23	Ginkgo biloba	1.00	1
24	glycyrrhiza uralensis	1.00	1
25	lilium lancifolium	1.00	1
26	litchi chinensis	1.00	1
27	lithospermum erythrorhizon	1.00	1
28	lobelia chinensis	1.00	1
29	lonicera japonica	1.00	1
30	morus alba	1.00	1
31	Nelumbo	1.00	1
32	Panax	1.00	1
33	panax notoginseng	1.00	1
34	perilla frutescens	1.00	1
35	pinellia ternata	1.00	1
36	Piper nigrum	1.00	1
37	platycodon grandiflorus	1.00	1
38	polygonum cuspidatum	1.00	1
39	Portulaca	1.00	1
40	prunella vulgaris	1.00	1
41	prunus armeniaca	1.00	1
42	prunus mume	1.00	1
43	Rubia	1.00	1
44	salvia miltiorrhiza	1.00	1
45	sargassum fusiforme	1.00	1
46	scutellaria baicalensis	1.00	1
47	smilax china	1.00	1
48	smilax glabra	1.00	1
49	Syzygium	1.00	1
50	verbena officinalis	1.00	1

Showing top 50 of 106 compounds. Use the BiohacksAI search to explore all NAMPT modulators.

About NAMPT as a Drug Target

NAMPT (Nicotinamide phosphoribosyltransferase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 106 compounds with documented NAMPT interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

NAMPT inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.