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Compounds That Target BACE1

beta-secretase 1 · 170 compounds in BiohacksAI corpus

BACE1 (beta-secretase 1) is a biological target with 170 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into BACE1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for BACE1
All 50 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Epigalocatechin Gallate
5.40
confidence
300+
studies
4.58
confidence
4
Cianidanol
4.52
confidence
5
Isoliquiritigenin
4.50
confidence
6
Morin
4.28
confidence
7
Amentoflavone
3.76
confidence
8
Tyramine
3.53
confidence
9
Acetoside
3.40
confidence
10
Pentosalen
3.37
confidence
11
Pentagalloyl Glucose
3.26
confidence
12
Morusin
2.94
confidence
13
Ly 2811376
2.94
confidence
14
7 Deazaxanthine
2.89
confidence
15
Hydroxytyrosol
2.83
confidence
16
Catechingallate
2.77
confidence
17
Memoquin
2.77
confidence
18
Ginkgetin
2.64
confidence
19
Kurarinone
2.48
confidence
20
Bilobetin
2.48
confidence
21
Verubecestat
2.48
confidence
22
Norartocarpetin
2.40
confidence
23
Sophoraflavanone G
2.30
confidence
24
Kuwanon C
2.30
confidence
25
Isoxanthohumol
2.30
confidence
26
Podocarpusflavone A
2.30
confidence
27
Gallocatechin
2.20
confidence
28
Isoginkgetin
2.20
confidence
29
Dieckol
2.08
confidence
30
Eckol
2.08
confidence
31
Sequoiaflavone
2.08
confidence
300+
studies
1.79
confidence
33
Mulberrofuran D
1.79
confidence
34
Phlorofucofuroeckol A
1.79
confidence
35
Grifolic Acid
1.79
confidence
36
Atabecestat
1.79
confidence
37
Ly 2886721
1.79
confidence
38
Grifolin
1.79
confidence
300+
studies
1.61
confidence
40
Myricetinflavonoids
1.61
confidence
300+
studies
1.39
confidence
43
Achyranthes Bidentata
1.00
confidence
44
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
46
Aloe Vera
1.00
confidence
47
Arctium Lappa
1.00
confidence
199+
studies
1.00
confidence
49
Artemisia Annua
1.00
confidence
50
Artemisia Argyi
1.00
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for BACE1 (beta-secretase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: BACE1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.