BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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B
MOLECULAR TARGETUniProt: P56817

BACE1

beta-secretase 1

170 compounds · BiohacksAI corpus v20260307-01

170
compounds
Compounds
170
Gene Symbol
BACE1
NCBI Gene
23621

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About BACE1

BACE1 (beta-secretase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 170 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View BACE1 on UniProt →
Compounds Targeting BACE1 (50)
1
Gefitinib
5.67
confidence
2
Epigalocatechin Gallate
5.40
confidence
300
studies
4.58
confidence
4
Cianidanol
4.52
confidence
5
Isoliquiritigenin
4.50
confidence
6
Morin
4.28
confidence
7
Amentoflavone
3.76
confidence
8
Tyramine
3.53
confidence
9
Acetoside
3.40
confidence
10
Pentosalen
3.37
confidence
11
Pentagalloyl Glucose
3.26
confidence
12
Morusin
2.94
confidence
13
Ly 2811376
2.94
confidence
14
7 Deazaxanthine
2.89
confidence
15
Hydroxytyrosol
2.83
confidence
16
Catechingallate
2.77
confidence
17
Memoquin
2.77
confidence
18
Ginkgetin
2.64
confidence
19
Kurarinone
2.48
confidence
20
Bilobetin
2.48
confidence
21
Verubecestat
2.48
confidence
22
Norartocarpetin
2.40
confidence
23
Sophoraflavanone G
2.30
confidence
24
Kuwanon C
2.30
confidence
25
Isoxanthohumol
2.30
confidence
26
Podocarpusflavone A
2.30
confidence
27
Gallocatechin
2.20
confidence
28
Isoginkgetin
2.20
confidence
29
Dieckol
2.08
confidence
30
Eckol
2.08
confidence
31
Sequoiaflavone
2.08
confidence
300
studies
1.79
confidence
33
Mulberrofuran D
1.79
confidence
34
Phlorofucofuroeckol A
1.79
confidence
35
Grifolic Acid
1.79
confidence
36
Atabecestat
1.79
confidence
37
Ly 2886721
1.79
confidence
38
Grifolin
1.79
confidence
300
studies
1.61
confidence
40
Myricetinflavonoids
0
studies
1.61
confidence
300
studies
1.39
confidence
43
Achyranthes Bidentata
1.00
confidence
44
Agastache Rugosa
1.00
confidence
500
studies
1.00
confidence
46
Aloe Vera
1.00
confidence
47
Arctium Lappa
1.00
confidence
199
studies
1.00
confidence
49
Artemisia Annua
1.00
confidence
50
Artemisia Argyi
1.00
confidence
Top 50 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.