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B
Domain Discovery

Muscle Performance & Recovery

Targets governing muscle protein synthesis, hypertrophy, and recovery. Compounds are ranked by target influence (IDF-weighted), research rarity, and momentum — revealing under-studied candidates with active signal.

Targets:MTORPRKAA1PRKAA2IGF1RMSTNPPARGC1AARESR1PPARGPPARA
783 compounds matched · 10 targets active

Top Emerging Muscle Performance & Recovery Compounds

#CompoundTop TargetsScoreStudies
1CentellaMSTN · IGF1R · PPARGC1A56.200199
2PortulacaMSTN · IGF1R · PPARGC1A56.148200
3SyzygiumMSTN · IGF1R · PPARGC1A56.148200
4Piper nigrumIGF1R · PPARGC1A · PRKAA249.641199
5NelumboMSTN · IGF1R · PPARGC1A46.790200
6RubiaMSTN · PPARGC1A · PRKAA245.421200
7FoeniculumPPARGC1A · PRKAA2 · PPARA43.531199
8curculigo orchioidesPPARGC1A · PRKAA2 · PPARA43.222116
9e guggulsteronePPARA · PPARG · ESR117.8990
10foretinibIGF1R · PRKAA2 · PRKAA115.7390
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50 compounds
#CompoundTargetsScoreStudiesEvid.
1
15% human
MSTNIGF1RPPARGC1APRKAA2+6
56.200
19931.6
2
9% human
MSTNIGF1RPPARGC1APRKAA2+6
56.148
20030.7
3
10% human
MSTNIGF1RPPARGC1APRKAA2+6
56.148
20030.6
4
7% human
IGF1RPPARGC1APRKAA2PPARA+5
49.641
19929.6
5
6% human
MSTNIGF1RPPARGC1APRKAA2+6
46.790
20031.1
6
6% human
MSTNPPARGC1APRKAA2PPARA+4
45.421
20029.8
7
13% human
PPARGC1APRKAA2PPARAPRKAA1+4
43.531
19932
8
2% human
PPARGC1APRKAA2PPARAPRKAA1+3
43.222
11628.7
9
PPARAPPARGESR1AR
17.899
0
10
IGF1RPRKAA2PRKAA1
15.739
0
11
IGF1RPRKAA2PRKAA1
15.739
0
12
IGF1RPRKAA2PRKAA1
15.739
0
13
IGF1RPRKAA2PRKAA1
15.739
0
14
IGF1RPRKAA2PRKAA1
15.739
0
15
IGF1RPRKAA2PRKAA1
15.739
0
16
IGF1RPRKAA2PRKAA1
15.739
0
17
IGF1RPRKAA2PRKAA1
15.739
0
18
IGF1RPRKAA2PRKAA1
15.739
0
19
Berberinecap
37% human
PRKAA2PPARAPRKAA1
15.079
46649.2
20
Rutincap
10% human
PRKAA2PPARGESR1
14.643
30038.6
21
7% human
MSTNIGF1RPPARGC1APRKAA2+5
13.449
2724.8
22
chrysincap
8% human
PPARGESR1AR
13.420
30037.2
23
6% human
MSTNPPARGC1APRKAA2PPARA+5
12.117
3624.9
24
8% human
IGF1RPPARGC1APRKAA2PPARA+5
11.845
3825.6
25
IGF1RPPARGC1APRKAA2PPARA+5
11.845
3829
score = target_influence × rarity × momentum⚡ acceleration >2×cap = ≥300 studies (corpus ceiling)click target chip to filter

About Muscle Performance & Recovery Compound Discovery

Discover emerging muscle performance compounds via mTOR, AMPK, IGF-1R, androgen receptor, and PGC-1α target networks. The discovery score combines three signals: target influence (how strongly a substance interacts with muscle performance & recovery targets, weighted by target specificity via IDF), rarity factor (inverse log of study count — fewer studies means higher discovery potential), and momentum factor (recent publication acceleration). Compounds with high scores represent mechanistically relevant, under-researched candidates with active research interest.

Key targets in this domain include: MTOR, PRKAA1, PRKAA2, IGF1, IGF1R, MSTN. The analysis covers 783 compounds from the BiohacksAI corpus of 4,824 substances derived from PubMed-indexed bioassay data.