Golgi Cisternae Pericentriolar Stack Reorganization

Q: What compounds affect the Golgi Cisternae Pericentriolar Stack Reorganization pathway?

43 compounds in the BiohacksAI corpus have documented interactions with genes in the Golgi Cisternae Pericentriolar Stack Reorganization pathway (Reactome ID: R-HSA-162658). These compounds target 6 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-1626586 genes43 compounds

The Golgi Cisternae Pericentriolar Stack Reorganization pathway (Reactome ID: R-HSA-162658) involves 6 genes and is affected by 43 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CCNB1 CCNB2 CDK1 MAPK1 MAPK3 PLK1

Compounds Affecting Golgi Cisternae Pericentriolar Stack Reorganization

#	Compound	Targets Hit	Studies
1	alsterpaullone	—	12
2	kenpaullone	—	8
3	fisetin	—	78
4	Sorafenib	—	300
5	indirubin	—	300
6	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
7	chrysin	—	300
8	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
9	plumbagin [Supplementary Concept]	—	300
10	pd98059	—	7
11	Clotrimazole	—	296
12	sp600125	—	117
13	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	—	300
14	Lithocholic Acid	—	300
15	trametinib	—	296
16	withaferin	—	300
17	Quercetin	—	300
18	tyrphostin ag 1478	—	4
19	Progesterone	—	299
20	2-Chloroadenosine 2-Chloroadenosine.	—	300
21	Benzalkonium Compounds	—	299
22	Calcimycin	—	216
23	daph	—	2
24	Diphenhydramine	—	14
25	ha1004	—	4
26	Loratadine	—	296
27	trequinsin hydrochloride	—	1
28	Clofibrate	—	299
29	Fenofibrate	—	297
30	Sertraline	—	1,000
31	Cinnarizine	—	299
32	Rotenone	—	300
33	ly294002	—	11
34	Wortmannin	—	300
35	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
36	Oleic Acid	—	112
37	Simvastatin	—	1,000
38	cefaclor	—	299
39	Disulfiram	—	297
40	Hexachlorophene	—	300
41	Nisoldipine	—	297
42	Oxyphenbutazone	—	300
43	Oxytetracycline	—	300

About the Golgi Cisternae Pericentriolar Stack Reorganization Pathway

The Golgi Cisternae Pericentriolar Stack Reorganization pathway is catalogued in Reactome (ID: R-HSA-162658) and involves 6 genes. In the BiohacksAI corpus, 43 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNB1, CCNB2, CDK1, MAPK1, MAPK3.