Question 1

What compounds affect the EPH-ephrin mediated repulsion of cells pathway?

Accepted Answer

28 compounds in the BiohacksAI corpus have documented interactions with genes in the EPH-ephrin mediated repulsion of cells pathway (Reactome ID: R-HSA-3928665). These compounds target 24 genes within this pathway.

Question 2

What genes are in the EPH-ephrin mediated repulsion of cells pathway?

Accepted Answer

The EPH-ephrin mediated repulsion of cells pathway involves 24 genes. Key genes include: ADAM10, APH1A, APH1B, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7.

#	Compound	Targets Hit	Studies
1	Sorafenib	—	300
2	Crizotinib	—	298
3	Dasatinib	—	299
4	Dihydroergocristine	—	187
5	tyrphostin ag 1478	—	4
6	Afatinib	—	297
7	kenpaullone	—	8
8	Quercetin	—	300
9	Axitinib	—	298
10	Kaempferols	—	300
11	pictilisib	—	25
12	alsterpaullone	—	12
13	sp600125	—	117
14	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
15	Cladribine	—	297
16	Pioglitazone	—	297
17	Vemurafenib	—	298
18	Resveratrol	—	298
19	Adenosine Monophosphate Adenine nucleotide containing	—	300
20	monorden	—	8
21	Niclosamide	—	299
22	Rosmarinic Acid	—	300
23	Genistein	—	300
24	egcg	—	300
25	Acetic Acid Product of	—	300
26	Bisphenol A-Glycidyl Methacrylate	—	197
27	Progesterone	—	299
28	Hexachlorophene	—	300

BiohacksAI

EPH-ephrin mediated repulsion of cells

Genes in this Pathway

Compounds Affecting EPH-ephrin mediated repulsion of cells

About the EPH-ephrin mediated repulsion of cells Pathway