What genes are in the NFE2L2 regulates pentose phosphate pathway genes pathway?

The NFE2L2 regulates pentose phosphate pathway genes pathway involves 5 genes. Key genes include: CREBBP, EP300, G6PD, NFE2L2, PGD.

NFE2L2 regulates pentose phosphate pathway genes

Q: What compounds affect the NFE2L2 regulates pentose phosphate pathway genes pathway?

209 compounds in the BiohacksAI corpus have documented interactions with genes in the NFE2L2 regulates pentose phosphate pathway genes pathway (Reactome ID: R-HSA-9818028). These compounds target 5 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-98180285 genes209 compounds

The NFE2L2 regulates pentose phosphate pathway genes pathway (Reactome ID: R-HSA-9818028) involves 5 genes and is affected by 209 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CREBBP EP300 G6PD NFE2L2 PGD

Compounds Affecting NFE2L2 regulates pentose phosphate pathway genes

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Quercetin	—	300
3	Nocodazole Nocodazole is	—	215
4	Papaverine	—	299
5	egcg	—	300
6	Resveratrol	—	298
7	Vitamin	—	295
8	Azacitidine	—	298
9	Azacitidine	—	300
10	Genistein	—	300
11	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
12	alpha-Linolenic Acid	—	300
13	Oxymetholone	—	298
14	Rotenone	—	300
15	Methylene Blue	—	200
16	Ethoxyquin Antioxidant; also	—	180
17	Nitrofurazone	—	300
18	Azathioprine	—	300
19	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
20	Mestranol	—	300
21	methoprene	—	300
22	Niclosamide	—	299
23	Phenelzine	—	2
24	vinblastine sulfate	—	81
25	chrysin	—	300
26	alyssin [Supplementary Concept]	—	300
27	Digitoxin	—	300
28	Digoxin	—	299
29	Flutamide	—	298
30	Hexachlorophene	—	300
31	Linoleic Acid	—	300
32	Vitamin K 3	—	300
33	Nitrofurantoin	—	297
34	Ouabain	—	300
35	Podophyllotoxin	—	14
36	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	—	299
37	Toxaphene	—	299
38	DEAD-box RNA Helicases	—	169
39	Thioctic Acid	—	298
40	amlexanox	—	96
41	Bortezomib	—	300
42	Chlormadinone Acetate	—	300
43	Ethidium	—	300
44	Feprazone	—	63
45	Idazoxan	—	300
46	Leflunomide	—	297
47	Oxyphenbutazone	—	300
48	Thioctic Acid	—	300
49	Caffeine	—	299
50	propyl gallate	—	261

About the NFE2L2 regulates pentose phosphate pathway genes Pathway

The NFE2L2 regulates pentose phosphate pathway genes pathway is catalogued in Reactome (ID: R-HSA-9818028) and involves 5 genes. In the BiohacksAI corpus, 209 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CREBBP, EP300, G6PD, NFE2L2, PGD.