BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Thiorphan

A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

300+ PubMed studies analyzed · 7 RCTs · Evidence Score: 44

Research Domains

Thiorphan has been studied across 23 research domains including 💊 Pain, 🏋️ Muscle & Hypertrophy, ❤️ Cardiovascular, 🫘 Kidney, 🫁 Respiratory. The primary research focus is 💊 Pain with 18% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Thiorphan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Demeclocycline
6 shared targets
darapladib
6 shared targets
2-Methoxyestradiol
7 shared targets
scriptaid
7 shared targets
Estrone
8 shared targets
Ticagrelor
6 shared targets
phosphoramidon
2 shared targets
Cisplatin
6 shared targets
Zearalenone
9 shared targets
omapatrilat
2 shared targets
Loading evidence profile...

This evidence profile for Thiorphan is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.