A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts produced in the myocardium, placenta, and uterus, but the cells of origin are not clear. Endothelin-2 has no unique physiologic functions, as compared with endothelin-1. (N Eng J Med 1995;333(6):356-63)
Endothelin 2 has been studied across 21 research domains including ❤️ Cardiovascular, 🔬 Oncology, 🫘 Kidney, 👁️ Vision & Eye, 🦴 Bone & Joint. The primary research focus is ❤️ Cardiovascular with 18% of studies addressing this area.
The following compounds share molecular targets with Endothelin 2, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Endothelin 2 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.