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Pentylenetetrazole

A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.

300+ PubMed studies analyzed · Evidence Score: 41.5

Research Domains

Pentylenetetrazole has been studied across 17 research domains including 🧘 Stress & Anxiety, 🧠 Memory, 🧠 Neuroprotection, 😴 Sleep, 🌤️ Mood & Depression. The primary research focus is 🧘 Stress & Anxiety with 13% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Pentylenetetrazole, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Chlorpheniramine
2 shared targets
Dizocilpine
2 shared targets
Piracetam
2 shared targets
Morphine
2 shared targets
Codeine
2 shared targets
Fentanyl
2 shared targets
Indomethacin
2 shared targets
2-Methoxyestradiol
2 shared targets
Bumetanide
2 shared targets
Glyburide
2 shared targets
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This evidence profile for Pentylenetetrazole is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.