A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Phenobarbital has been studied across 13 research domains including 🫁 Liver & Detox, 😴 Sleep, 🧠 Focus & Attention, 🔥 Metabolic, 🔬 Oncology. The primary research focus is 🫁 Liver & Detox with 12% of studies addressing this area.
The following compounds share molecular targets with Phenobarbital, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Phenobarbital is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.