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Lamotrigine

A phenyltriazine compound, sodium and calcium channel blocker that is used for the treatment of SEIZURES and BIPOLAR DISORDER.

296+ PubMed studies analyzed · 12 RCTs · Evidence Score: 46.7

Research Domains

Lamotrigine has been studied across 14 research domains including 🧘 Stress & Anxiety, 🌤️ Mood & Depression, 💊 Pain, 🫁 Liver & Detox, 😴 Sleep. The primary research focus is 🧘 Stress & Anxiety with 5% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Lamotrigine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Phenytoin
7 shared targets
Nateglinide
5 shared targets
Aztreonam
4 shared targets
Pinacidil
4 shared targets
Midodrine
4 shared targets
Phenobarbital
5 shared targets
Iproniazid
5 shared targets
Cefoperazone
5 shared targets
Metaraminol
4 shared targets
Modafinil
4 shared targets
Loading evidence profile...

This evidence profile for Lamotrigine is generated deterministically from 296 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.